Axokine (Regeneron) - PubMed
Axokine, a second-generation neurotrophic factor that is related to ciliary neurotrophic factor (CNTF), is under development by Regeneron for the potential treatment of obesity and …
Nature亮点 | 人工合成细胞因子有望用于治疗2型糖尿病 - 知乎
而对于CNTF而言，尽管人源的CNTF—Axokine已经被用于治疗肌萎缩性侧束硬化(amyotrophic lateral sclerosis)的临床试验,但人们发现在治疗过程中体内会产生相应的抗体【4】，由于担心 …
Ciliary neurotrophic factor - Wikipedia
A recombinant version of human CNTF (rhCNTF), trade name Axokine, is a modified version with a 15 amino acid truncation of the C-terminus and two amino acid substitutions. It is three to …
Axokine: Uses, Dosage, Side Effects, Food Interaction & FAQ
2025年1月7日 · Axokine is a 4-aminoquinoline antimalarial with actions similar to those of chloroquine but is mainly used in the treatment of SLE and rheumatoid arthritis. It interferes …
Survey Ciliary neurotrophic factor (CNTF): New facets of an old ...
2015年10月1日 · Axokine (Regeneron Pharmaceuticals, Inc., Tarrytown, NY) is a recombinant variant of human CNTF (rvhCNTF). In Axokine, the last carboxy 15 amino acids are truncated, …
Regeneron：两个人和一个生物制药公司的传奇故事 - 丁香园
2014年10月22日 · 1999年，Regeneron启动了在研药物AXOKINE用于肥胖症的临床研究，然而不幸的是这款产品在6年后仍然再蹈覆辙止步于III期临床试验。 这一系列的“滑铁卢”不免令人失 …
Central Administration of the Ciliary Neurotrophic Factor Analogue ...
Methods: The CNTF analogue, Axokine, was infused into the lateral ventricle of high-fat-fed mice for 1 week. Food intake, energy expenditure, body mass, glucose metabolism, and …
睫状神经营养因子 - 百度百科
睫状神经营养因子 (CNTF)类似物，CNTF可以模仿瘦素在下丘脑的效应，也成为减肥药研究的重要靶点之一。 正在开发的这类药物如美国Regeneron公司的Axokine。 该药为CNTF经基因工程 …
Axokine® Hidroxicloroquinasulfato Comprimidosrecubiertos VentaBajoReceta IndustriaArgentina COMPOSICIÓN Cadacomprimidorecubiertocontiene ...
Axokine drug & pharmaceuticals. Axokine available forms, doses, …
Axokine is indicated for the suppressive treatment and treatment of acute attacks of malaria due to Plasmodium vivax, P. malariae, P. ovale, and susceptible strains of P. falciparum. It is also …