The Martin XB-51 was an American trijet ground-attack aircraft. It was designed in 1945 and made its maiden flight in 1949. It was originally designed as a bomber for the United States Army Air Forces under specification V-8237-1 and was designated XA-45.

HLA-B51 (B51) is an HLA-B serotype. The serotype identifies the more common HLA-B*51 gene products. [1] B51 is a split antigen of the broad antigen B5, and is a sister serotype of B52. [2] There are many alleles within the B*51 allele group. B51 is associated with several diseases, including Behçet's disease.

HLA-B∗51 remains the most important genetic factor in Behçet's syndrome, despite the recent identification of several susceptibility genes. The prevalence of HLA-B∗51 has been shown to differ among phenotype-based clinical clusters in the same patient population.

Behcet Disease (BD) is a rare, chronic, multisystem disease caused by vasculitis of blood vessels throughout the body. The disease course is marked by recurrent ulcers of the oral and genital regions, often with severe ocular inflammation that may lead to visual impairment or blindness.

To quantify by meta-analysis the genetic effect of the HLA–B5 or HLA–B51 (HLA–B51/B5) allele on the risk of developing Behçet’s disease (BD) and to look for potential effect modifiers. Relevant studies were identified using the PubMed Medline database and manual searches of …

2012年10月6日 · Martin’s two XB-51 prototypes, seen low over the runway on a high speed pass. The only two XB-51s ever made, both were eventually lost in crashes attributed to pilot error. U.S. Air Force photo.

Several versions of the HLA-B gene, particularly HLA-B51, are associated with an increased risk of developing Behçet disease, a chronic inflammatory condition that affects many parts of the body. This association is strongest in people from Japan, the Middle East, and other parts of Asia.

B51 or B-51 may refer to: HLA-B51, an HLA-B serotype; Bundesstraße 51, a road in western Germany; Martin XB-51, an American airplane; Sicilian Defence, in the Encyclopaedia of Chess Openings; B51 (New York City bus)

2024年5月3日 · HLA-B*51 is strongly associated with BD with approximately 60% of patients being positive, as opposed to about 15% positivity in healthy individuals across different ethnicities. Due to low specificity, HLA-B*51 positivity is not diagnostic for BD.

Behçet’s disease (BD) is a complex, recurring inflammatory disorder with autoinflammatory and autoimmune components. This comprehensive review aims to explore BD’s pathogenesis, focusing on established genetic factors.