YAP1 - Wikipedia
YAP1 (yes-associated protein 1), also known as YAP or YAP65, is a protein that acts as a transcription coregulator that promotes transcription of genes involved in cellular proliferation …
Moreover, the relationship between YAP1 and PD-L1 revealed the important role of YAP1 in im-munotherapy against NSCLC. Further, preclinical studies reported roles of verteporfin, one …
ACAT2 suppresses the ubiquitination of YAP1 to enhance the ...
2024年4月26日 · Increased YAP1 protein expression remarkably activated the YAP1/TAZ-TEAD1 signaling pathway, which further boosted the malignant phenotypes in GC cells. In conclusion, …
癌蛋白YAP1的研究进展 - pibb.ac.cn
Yes相关蛋白1 (Yes-associated protein 1，YAP1)是Hippo信号通路 (Hippo pathway)中的一个分子．早期研究人员发现，在Hippo信号通路正常的情况下，YAP1处于非激活状态；当Hippo信号 …
【cell子刊】小分子共价修饰导致TEAD⋅Yap蛋白-蛋白质相互作用的 …
河马信号主要调节Yap1结合 TEA domain family member （TEAD）转录因子的能力。 Yap1通过大的扁平界面与TEAD4紧密结合，这使得小分子正构抑制剂的开发极具挑战性。 在此，我们 …
<br>YAP1-TEAD1-Glut1 轴通过调节糖酵解来决定乳腺癌细胞的致 …
In this study, by loss-of-function assay, we demonstrated that YAP1 contributed to the glycolytic phenotype of breast cancer cells. Knockdown of YAP1 inhibited the extracellular acidification …
<br>YAP1 识别炎症和机械信号，通过促进细胞存活和纤维化加剧 …
人们正在研究 yes 相关蛋白 1 (YAP1)（一种器官大小控制器和机械转导器）是否与炎症诱导的 BPH 有关。 分析了人和大鼠 BPH 标本中 YAP1 表达与纤维化之间的相关性。
YAP1 Gene - GeneCards | YAP1 Protein | YAP1 Antibody
2024年12月25日 · YAP1 (Yes1 Associated Transcriptional Regulator) is a Protein Coding gene. Diseases associated with YAP1 include Coloboma, Ocular, With Or Without Hearing …
<br>YAP1在肝癌干细胞中的作用：已证实的和潜在的机 …
2022年6月7日 · YAP1（Yes 相关蛋白 1）是通过充当基因表达驱动因子来介导肿瘤发生的主要因素之一。 已被证实在器官体积控制、干细胞功能、组织再生、肿瘤发生和肿瘤转移中发挥重 …
β-Catenin-Driven Cancers Require a YAP1 Transcriptional …
2012年12月21日 · Loss-of-function screens and β-catenin activity profiling in 85 cancer cell lines identified a transcriptional complex composed of YAP1, a known mediator of Hippo signaling, …