Learn more about our clinical trial (NCT06706076) at clinicaltrials.gov. BH-30236-01: Phase 1 Clinical Trial for a Multi-targeted CLK Inhibitor in Relapsed or Refractory Adult Acute Myeloid Leukemia (AML) and Higher-Risk Myelodysplastic Syndrome (HR-MDS)

Medicines built from the ground up that aim to overcome the limitations of existing therapies. Explore our clinical trials and learn about how you can participate.

BH Trials is an obstacle course game where players drive a Backhoe digger with no transmission, steering, or brakes: the only way to control it is through the digger’s arms. The game features several game modes with varied challenges both in single player and up to 4 player Co-op.

We are evaluating a potentially better way to treat EGFR-positive NSCLC. BH-30643 is a mutant-selective OMNI-EGFR ™ inhibitor with an aim to provide greater benefit to patients by: Super-high potency against common, atypical and compound EGFR mutations, including those induced by treatment with other EGFR inhibitors.

Study BH-30236-01 is a first-in-human (FIH), Phase 1/1b, open-label, dose escalation and expansion study in participants with relapsed/refractory acute myelogenous leukemia (R/R AML) or higher-risk myelodysplastic syndrome (HR-MDS).

2025年1月23日 · The Phase 1/2 SOLARA clinical trial evaluates BH-30643, a macrocyclic, reversible, mutant-selective OMNI-EGFR™ inhibitor for patients with locally advanced or metastatic non-small cell lung cancer (NSCLC) bearing EGFR or HER2 mutations.

2025年1月22日 · bh-30643 是一种宏环状、可逆、突变选择性的omni-egfr™抑制剂。 它在预销试验中展示了强大的抗肿瘤活性，覆盖了经典EGFR突变（如缺失19号外显子、L858R）、非经典EGFR突变（如G719X、L861Q、S768I等）、20号外显子插入以及HER2突变。

Take the backhoe to the goal of each level, try to avoid breaking anything on your way and find the hidden toys. Up to four players, four arms, but only one digger. Collaborate to move this …

Uncover everything you need to train your dog for your upcoming BH trial! Master the rules, trial etiquette, and a simplified modern schutzhund training system for crafting an extraordinary BH routine. Tap into trial tips and tricks from a seasoned handler with a track record spanning BH titles to IGP National Championships over the last 18 years.

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