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2020年10月6日 · PET/CT can detect more bone marrow involvement in lymphoma compared with BMB. It can replace the routine invasive BMB in many cases, especially those showing multifocal uptake in both Hodgkin and non-Hodgkin lymphoma. PET/CT can also help to guide the site of the biopsy in some cases.

Bone marrow examination refers to the pathologic analysis of samples of bone marrow obtained by bone marrow biopsy (often called trephine biopsy) and bone marrow aspiration. Bone marrow examination is used in the diagnosis of a number of conditions, including leukemia, multiple myeloma, lymphoma, anemia, and pancytopenia.

2021年1月30日 · Initial staging by positron emission tomography/computed tomography (PET/CT) scanning is recommended for patients with diffuse large B-cell lymphoma (DLBCL). Whether both PET/CT and bone marrow biopsy (BMB) are required remains unclear. This study examined whether staging by PET/CT is sufficient.

Evaluation of bone marrow involvement (BMI) is paramount in diffuse large B-cell lymphoma (DLBCL) for prognostic and therapeutic reasons. PET/CT scanner (PET) is now a routine examination for the staging of DLBCL with prognostic and therapeutic implications.

2013年7月4日 · The main objective of the present study by Khan et al 1 was to determine whether routine BMB could also be omitted at diagnosis in patients with DLBCL staged by FDG–PET-CT scan, as shown in newly diagnosed patients with HL. This retrospective study provides valuable data on the power of FDG–PET-CT scanning in detecting focal BM involvement ...

Bone marrow biopsy (BMB) is a routinely used diagnostic and staging modality, in conjunction with imaging methods in patients with lymphoma. 18F-fluoro-2-deoxy-D-glucose (FDG) positron emission tomography-computed tomography (PET/CT) is an imaging modality that is increasingly used for the initial staging of lymphoma patients, with previous stud...

2023年2月12日 · The gold standard method used for the identification of bone marrow involvement is bone marrow biopsy (BMB), but it has certain drawbacks. In recent years, positron emission tomography/computed tomography (PET/CT) has become a highly effective method in the diagnosis and staging of lymphoma.

2017年12月7日 · Recent studies have suggested that PET-CT scans can detect BM involvement in most patients with lymphoma. As such, there is growing interest into whether or not PET-CT scans may replace the need for BMB in staging patients with lymphoma.

The gold standard procedure for evaluating BMI is bone marrow biopsy (BMB) . However, BMB explores only a limited part of the bone marrow, generally the unilateral or bilateral iliac crest, so focal bone marrow involvement may be missed. In addition, as an invasive procedure, BMB can cause pain to patients . Despite these defects, BMB has been ...