2021年12月1日 · What you should cover. The International Continence Society defines OAB as “urinary urgency, usually accompanied by urinary frequency and nocturia, with or without urgency urinary incontinence, in the absence of urinary tract infection or other obvious pathology.” 7 The diagnostic process therefore aims to characterise the lower urinary tract symptoms experienced …

2012年4月17日 · #### Summary points In 2010, the International Continence Society restated the definition of overactive bladder syndrome as a condition with characteristic symptoms of “urinary urgency, usually accompanied by frequency and nocturia, with or without urgency incontinence, in the absence of urinary tract infection or other obvious pathology.”1 In 2009, disease specific total expenditures for ...

2022年9月27日 · BMJ Medicine is an open access, multispecialty journal from The BMJ. BMJ Medicine is an international multispecialty journal that promotes multidisciplinary collaboration through encouraging scientific debate, and the exchange of new knowledge and ideas. Closely aligned with The BMJ, BMJ Medicine prioritises high impact research, specialist reviews, and diverse research methods papers with the ...

2012年3月27日 · A 45 year old woman presents to her general practitioner complaining of troublesome urinary symptoms increasingly affecting her quality of life. She is currently voiding more than 10 times a day and rising three times at night. In addition she notices a sudden urgent desire to void and on two occasions has leaked urine before reaching the toilet. She gives no history of urinary tract infection ...

BMJ Open. 2018 Nov 21;8(11):e021889. doi: 10.1136/bmjopen-2018-021889. ... Most patients with OAB discontinued oral OAB pharmacotherapy and were non-adherent 1 year after treatment initiation. In general, mirabegron was associated with greater persistence and adherence compared with antimuscarinics. Combined with existing clinical trial ...

Objective To investigate whether different anticholinergic drug treatments for overactive bladder have differential risks for incident dementia, in a large representative population of older adults in England.Design Nested case-control study.Setting General practices in England providing data to the Clinical Practice Research Datalink (CPRD) GOLD database, with …

Overactive bladder (OAB is a definition by the International Continence Society (ICS). It comprises three symptoms, urge, frequency and nocturia. OAB is a major problem for up to 30% of women, more so for elderly women. OAB is generally assumed to be a paradigm, but it cannot meet the criteria of a paradigm, as its causation

Conclusion Most patients with OAB discontinued oral OAB pharmacotherapy and were non-adherent 1 year after treatment initiation. In general, mirabegron was associated with greater persistence and adherence compared with antimuscarinics. Combined with existing clinical trial evidence, this real-world review merits consideration of mirabegron for first-line pharmacological treatment among ...

BMJ. AbstrACt Purposeo evaluate persistence and adherence of oral T pharmacotherapy used in the treatment of overactive bladder (OAB) in a real-world setting. Materials and methods Systematic literature searches of six electronic publication databases were performed to identify observational studies of patients with OAB treated

Context OnabotulinumtoxinA and mirabegron have recently gained marketing authorisation to treat symptoms of overactive bladder (OAB). Objective To evaluate the relative efficacy of mirabegron and onabotulinumtoxinA in patients with idiopathic OAB. Design Network meta-analysis. Data sources A search of 9 electronic databases, review documents, guidelines and websites. Methods Randomised trials ...