2022年7月18日 · Bone remodeling defines the primary activities that BMUs need to perform to renew successfully bone structural units.

This process, called bone remodeling, is accomplished by assembly of osteoclasts and osteoblasts into discrete temporary anatomic structures called basic multicellular units …

2024年2月1日 · Bone tissue in the adult skeleton is continuously renewed via the remodeling process. A transient collection of cells, known as a basic multicellular unit (BMU), work in a …

A bone remodeling unit (BRU) or basic multicellular unit (BMU) is defined as a group of bone cells that removes and replaces one bone structural unit (osteon or hemiosteon) (see Figure 13-12).

Bone remodeling defines the primary activities that BMUs need to perform to renew successfully bone structural units.

In bone physiology, the bone remodeling period describes the temporal duration (i.e. lifespan) of the basic multicellular unit (BMU) that is responsible for bone turnover. Historically, this was …

The activity of basic multicellular units (BMU) in cortical bone is classically described as a sequential order of events- resorption, reversal and formation. This simplified portrayal of the …

BMUs are transient functional grouping of cells that progress through the bone, removing old bone and replacing it with new bone.

We propose in this work a minimal model of BMU function that involves a limited number of signals able to account for fully functional BMU operation.

According to Parfitt (1980), resorption in the BMU of adult bone takes about 3 weeks and bone formation takes 3-4 months. Overall, about 5-10% of the skeleton is replaced each year, and …