布鲁顿酪氨酸激酶（Bruton’s tyrosine kinase，BTK）是胞浆内非受体型酪氨酸激酶TEC家族中的一员，在B细胞生长发育、增殖分化过程中起着重要作用，同时也是B细胞恶性肿瘤的治疗靶点。

Bruton's tyrosine kinase (BTK) is a TEC kinase with a multifaceted role in B-cell biology and function, highlighted by its position as a critical component of the B-cell receptor signalling …

Bruton's tyrosine kinase (abbreviated Btk or BTK), also known as tyrosine-protein kinase BTK, is a tyrosine kinase that is encoded by the BTK gene in humans. BTK plays a crucial role in B …

2018年2月19日 · In this review, we discuss the role of BTK in B cell differentiation and B cell malignancies and highlight the importance of BTK inhibition in cancer therapy. Bruton’s …

2014年3月24日 · Bruton's tyrosine kinase (BTK) is a key component of B cell receptor (BCR) signalling and functions as an important regulator of cell proliferation and cell...

2024年2月22日 · Bruton酪氨酸激酶（BTK）是一种非受体激酶，在许多B细胞恶性肿瘤中扮演关键的致癌信号传导作用，对白血病细胞的增殖和存活至关重要。 BTK最初在 X连锁遗传无球蛋白 …

2018年2月19日 · Bruton's tyrosine kinase (BTK) is a non-receptor kinase that plays a crucial role in oncogenic signaling that is critical for proliferation and survival of leukemic cells in many B …

2024年11月1日 · Bruton tyrosine kinase (BTK) is a key node mediating signal transduction downstream of the BCR. The advent of BTK inhibitors has revolutionized the treatment …

BTK，即 布鲁顿酪氨酸激酶，是一种非受体酪氨酸激酶，在B淋巴细胞的发育和激活中发挥重要作用。 BTK抑制剂通过抑制BTK的活性来控制肿瘤的生长和转移。 目前市场上有多种BTK抑制 …

Bruton tyrosine kinase (BTK) is a key signalling molecule in the B-cell receptor pathway which is important for B-cell proliferation and survival. The development of drugs which inhibit BTK has …