BAG family molecular chaperone regulator 3 is a protein that in humans is encoded by the BAG3 gene. BAG3 is involved in chaperone-assisted selective autophagy. [5][6][7][8][9] BAG …

2024年12月24日 · BAG3 (BAG Cochaperone 3) is a Protein Coding gene. Diseases associated with BAG3 include Myopathy, Myofibrillar, 6 and Cardiomyopathy, Dilated, 1Hh. Among its …

摘 要:Bcl2 相关永生基因3(BAG3) 被鉴定为抗凋亡和前自噬因子,包含BAG、WW 和PXXP三个结构域。 BAG3与多种蛋白相互作用,被多种信号激活,又能激活多种信号通路,调控多种生理和病理 …

2011年4月7日 · Bcl2-associated athanogene 3 (BAG3) protein is a member of BAG family of co-chaperones that interacts with the ATPase domain of the heat shock protein (Hsp) 70 through …

2011年4月7日 · Bcl2-associated athanogene 3 (BAG3) protein is a member of BAG family of co-chaperones that interacts with the ATPase domain of the heat shock protein (Hsp) 70 through...

2024年2月23日 · BAG3（BCL2-associated athanogene-3）是一种重要的分子伴侣蛋白，在细胞应激、凋亡和信号转导等生物学过程中发挥着重要作用。 最近，研究人员成功地制备了BAG3 …

bag3是一种多功能hsp70伴侣蛋白和抗凋亡蛋白，可通过其c端bag结构域与hsp70的atpase结构域相互作用，在细胞蛋白水解中起着关键的生理作用。 HSP70 / BAG3复合物通过两种主要的蛋 …

We describe BAG3 as a quintessential multi-functional protein. It supports autophagy of both misfolded proteins and damaged organelles, inhibits apoptosis, maintains the homeostasis of …

2023年3月19日 · We describe BAG3 as a quintessential multi-functional protein. It supports autophagy of both misfolded proteins and damaged organelles, inhibits apoptosis, maintains …

2020年8月1日 · BAG3 protein modulates multiple pathways involved into cell stress response. Apoptosis, autophagy, cytoskeleton dynamics are regulated by BAG3. BAG3 supports cell …