BCKDHA is a coding gene that is part of the BCKD complex (branched-chain alpha-keto acid dehydrogenase). BCKDHA was discovered by John Menkes in 1954. After he had seen a …

The BCKDHA gene provides instructions for making one part, the alpha subunit, of a group of enzymes called the branched-chain alpha-keto acid dehydrogenase (BCKD) enzyme complex. …

2025年2月8日 · A list of nine primary candidate genes for T2D and five for obesity were identified in this paper. Two genes, LPL and BCKDHA, were common to these two sets. BCKDHA and …

2024年12月24日 · BCKDHA (Branched Chain Keto Acid Dehydrogenase E1 Subunit Alpha) is a Protein Coding gene. Diseases associated with BCKDHA include Maple Syrup Urine Disease, …

支链α-酮酸 (BCAA) 脱氢酶 (BCKD) 复合物是一种线粒体内酶复合物，可催化支链氨基酸亮氨酸、异亮氨酸和缬氨酸分解代谢的第二个主要步骤。 BCKD 复合物由三个催化组分组成：异四聚 …

2024年10月10日 · The rate limiting enzyme of BCAA catabolism branched-chain α-ketoacid dehydrogenase (BCKDH) is phosphorylated at E1α subunit (BCKDHA) by its kinase (BCKDK) …

2024年10月10日 · Elevated circulating branched-chain amino acids (BCAAs) are tightly linked to an increased risk in the development of type 2 diabetes mellitus. The rate limiting enzyme of …

BCAA降解的第二步是BCKA不可逆脱羧，由线粒体中的支链α-酮酸脱氢酶（BCKDH）复合体催化。 BCKDH复合体的活性取决于它的磷酸化状态，由支链α-酮酸脱氢酶激酶（BCKDK） …

2025年2月8日 · The branched-chain alpha-keto acid (BCAA) dehydrogenase (BCKD) complex is an innter mitochondrial enzyme complex that catalyzes the second major step in the …

2009年11月2日 · The BCKDHA gene encodes the E1-alpha subunit of the branched-chain alpha-keto acid (BCAA) dehydrogenase complex (BCKD; EC 1.2.4.4), an inner-mitochondrial …