2024年12月24日 · BCLAF1 (BCL2 Associated Transcription Factor 1) is a Protein Coding gene. Diseases associated with BCLAF1 include Emery-Dreifuss Muscular Dystrophy and Uterine …

摘 要:BCLAF1 (Bcl2 associated transcription factor 1 ,又称为BTF) 最初被鉴定为与BCL2家族的抗凋亡成员相互作用的蛋白质。 初步研究表明,该蛋白具有细胞凋亡诱导因子和转录抑制因子的 …

该基因编码一个转录抑制因子，该抑制因子与 BCL2 蛋白家族的几个成员相互作用。 该蛋白的过表达会诱导细胞凋亡，而细胞凋亡可通过共表达 BCL2 蛋白来抑制。 该蛋白质定位于整个细胞 …

2016年1月22日 · Here, we reveal Bcl-2-associated transcription factor 1 (Bclaf1) as a novel player in the therapeutic drug doxorubicin-induced senescence (TIS) in multiple cancer cells. Bclaf1 …

Bcl-2-associated transcription factor 1 is a Bcl-2 family protein in humans that is encoded by the BCLAF1 gene. [5] [6] [7] This gene encodes a transcriptional repressor that interacts with …

2014年8月5日 · Bcl-2-associated transcription factor 1 (BCLAF1) has been reported to be involved in diverse biological processes. It was initially identified as a protein partner for the...

Originally identified as a regulator of apoptosis and transcription, B-cell lymphoma-2-associated transcription factor 1 (BCLAF1) has since been shown to be associated with a multitude of …

Bclaf1 is a direct target of HIF-1 and critically regulates the stability of HIF-1alpha under hypoxia. Study identified Bcl2-associated factor 1 (BCLAF1) as a phosphorylation-dependent SDS22 …

2019年1月25日 · Type I interferon response plays a prominent role against viral infection, which is frequently disrupted by viruses. Here, we report Bcl-2 associated transcription factor 1 (Bclaf1) …

Bcl-2-accociated transcription factor 1（BCLAF1） is a multi-functional protein containing a serine/arginine-rich domain（RS domain） and DNA binding domains. It has been involved in …