BerEp4 (also Ber-EP4) is a histologic stain mainly used to aid in the diagnosis of basal cell carcinoma (BCC). [2] It is an antibody to EpCAM (epithelial cell adhesion molecule). [1]

BerEP4 is a monoclonal antibody which detects specific epithelial-glycoprotein-adhesion-molecules (EpCAM) found on BCC cells. Various studies have shown that BerEP4 has a high sensitivity and specificity in detecting only BCC cells.

Ber-EP4 is a useful diagnostic marker for BSCC, positive in 82% (37/45) of the cases and in 68% (23/34) of SCC. An alternative is the combination of cytokeratins CK14 and CK7, known to be negative, and CK1, known to be positive, which achieves an accuracy of 73% (33/45) in BSCC and 88% (30/34) in SCC.

Ber -EP4 is a mouse monoclonal antibody that is intended for laboratory use in the qualitative identification of the cell surface glycoprotein known as Epithelial Antigen by immunohistochemistry (IHC) in formalin-fixed paraffin-

2021年4月1日 · We reviewed all articles on Ber-EP4 staining in effusion cytology, summarized current findings and analyzed the staining pattern of all cases expressing Ber-EP4. Some cases showing Ber-EP4 positivity in mesothelium have been reported, most of which showed only weak Ber-EP4 staining or staining of less than 50% of mesothelial cells.

Ber-EP4 is an immunohistochemical (IHC) marker used to detect the presence of epithelial cells in tissue samples. 1 It is a monoclonal antibody that recognizes a glycoprotein called epithelial cell adhesion molecule (EpCAM), which is expressed on the surface of most epithelial cells, the

Immunohistochemical examination using the Ber-EP4 antibody is a useful tool for diagnosing neoplasms with follicular germinative differentiation, such as TB, TE or BCC, and for differentiating those from squamous cell carcinoma in situ, poroma or seborrheic keratosis.

2016年5月15日 · Ber-EP4 is a commonly available immunostain. It is directed against EpCam. [1] Basal cell carcinoma. Lung adenocarcinoma (55 positive of 59 cases [2]). Squamous cell carcinoma of the skin. [3] Malignant mesothelioma (18 positive of 70 cases [2]). Microcystic adnexal carcinoma. [4] Immunohistochemistry. MOC31. ↑ Dasgeb, B.; Mohammadi, TM.;

2017年12月31日 · This review aims to evaluate studies on the use of BerEP4 immunohistochemistry staining on pathological sections of various types of BCC as well as its shortfalls. BerEP4 is a monoclonal antibody...

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