Epigenetics and cell cycle regulation in cystogenesis - PMC
PKD epigenetics is the study of somatically heritable changes in DNA methylation, histone modifications and genes encoding epigenetic modifiers by comparison between normal cells …
Therapeutic targeting of BET bromodomain protein, Brd4, delays …
In this study, we identified a BET bromodomain (BRD) protein, Brd4, not only as a novel epigenetic regulator of autosomal dominant polycystic kidney disease (ADPKD) but also as a …
Gene therapy in polycystic kidney disease: A promising future
2025年1月10日 · Polycystic kidney disease (PKD) is a genetic disorder marked by numerous cysts in the kidneys, progressively impairing renal function. It is classified into autosomal …
Can ketogenic dietary interventions slow disease progression in …
Autosomal dominant polycystic kidney disease (ADPKD) is the most common inherited kidney disease leading to kidney failure. To date, there is no cure for the disease although there is …
Patient Knowledge Distillation for BERT Model Compression
2019年8月25日 · Pre-trained language models such as BERT have proven to be highly effective for natural language processing (NLP) tasks. However, the high demand for computing …
BERT-PKD: BERT模型压缩之耐心知识蒸馏（2019.08） - 知乎专栏
BERT12(teacher)是我们自己的BERTteacher模型的实现。 FT表示在不使用知识蒸馏的情况下对每个数据集进行直接微调。 KD代表使用最原始的知识蒸馏法。 PKD代表我们提出的Patient-KD …
PKD-Bert：基于多层网络的Bert知识蒸馏 - CSDN博客
2020年11月30日 · 接下来，我们从PKD模型的两个策略说起：PKD-Last 和 PKD-Skip。 1.PKD-Last and PKD-Skip. PKD的本质是从中间层学习知识，但是这个中间层如何去定义，就各式各 …
pKD46 vector and functional exo, bet & gam genes.
Download scientific diagram | pKD46 vector and functional exo, bet & gam genes. from publication: Improvment Of Homologous Recombination efficiency in E.coli | …
Feasibility and impact of ketogenic dietary interventions in …
Ketogenic dietary interventions (KDIs) are beneficial in animal models of autosomal-dominant polycystic kidney disease (ADPKD). KETO-ADPKD, an exploratory, randomized, controlled …
Sodium–glucose cotransporter inhibition in polycystic kidney disease ...
2022年1月31日 · The possible beneficial effects of SGLTi on polycystic kidney disease (PKD) are shown with green arrows as they can interfere in multiple pathological processes of PKD by …