In geometry and mathematical biology, a biconcave disc — also referred to as a discocyte[1] — is a geometric shape resembling an oblate spheroid with two concavities on the top and on the bottom. Biconcave discs appear in the study of cell biology, as an approximation to the shape of certain cells, including red blood cells.

2016年12月5日 · The shape of the human red blood cell is known to be a biconcave disk. It is evident from a variety of theoretical work that known physical properties of the membrane, such as its bending energy and elasticity, can explain the red-blood-cell biconcave shape as well as other shapes that red blood cells assume.

The human erythrocyte adopts a distinctive biconcave disc form in vivo. The question as to why the red blood cell should have this particular profile remains unresolved. It has been suggested that this shape maximises the surface area to volume ratio and thus expedites diffusion.

In the vast majority of mammalian species , the typical shape is the biconcave disc, flattened and depressed in the center, with a torus-shaped rim on the edge of the disc and with a dumb bell-shaped cross section . Its distinctive biconcave shape results in a high surface-area-to-volume (SA/V) ratio (human RBCs, for example, show a 40% excess ...

2006年1月1日 · The biconcave disc form distributes much of the volume and hence mass of the red blood cell to the periphery and therefore increases a quantity, know as the moment of inertia of the red blood cell. The moment of inertia describes the distribution of mass of a body around a particular axis and is given by ∑ mr 2 .

2019年12月24日 · In mammals, their main role is to transport oxygen to all parts of a body’s tissue. The normal shape of RBCs is a biconcave discoid (Fig. 1b) which can be transformed in other shapes, such as...

2023年8月22日 · RBCs are biconcave disk shape cells with special physical features. The biconcave disk shape increases RBC surface area and its deformability [ 13 ]. Their surface area of 140 µm 2 exhibits an excess surface area of 40% compared with a sphere of the same volume.

The normal shape of a red blood cell, one that picks up oxygen in the lungs and transports it to the body cells, is that of a biconcave disc (Figure 2.5 (a)). This shape is necessary because it allows many to pack closely together without clogging the very fine blood vessels (called capillaries) that deliver the blood to the organs all over the ...

2019年11月2日 · Red blood cells or erythrocytes or RBCs are small, biconcave disks that are, a disk thicker at the edges than in the middle, like a doughnut with a center depression on each side instead of a hole. This shape and their small size (7 micrometers in diameter) impart to the erythrocytes a high surface-to-volume ratio so that oxygen and carbon ...

2016年11月26日 · Why are red blood cells biconcave? Mammalian RBC's are typically shaped as biconcave discs i.e. flattened and depressed in the centre , with a dumb bell shaped cross section. This distinctive biconcav shape optimises the flow properties of blood in the large vessels.