2023年10月12日 · Note that CIS has not progressed beyond the basement epithelial layer of the lining of the bladder, and CIS cancer cells are sticking together. But without treatment such as by BCG or GEM/DOC, CIS caners are known to progress to the connective tissue and muscle tissue.

2025年1月17日 · Having said that AUA defines CIS as high risk NIMBC, and for high risk NMIBC, AUA suggests 3 years of BCG treatment. So, your thought of continuing BCG is in the right direction as long as your side effects can be managed. This is where the art of managing BCG side effects come in. Give time for bladder to heal, then continue with BCG.

2020年8月1日 · I had CIS in Jan 2019, After TURBIT (it healed), biopsies showed that cancer was in other places in the bladder. Wenet through 6 BCG treatments in 2019 but it did not help. RC/IC in August 2019, and found out that cancer went from t0 (in Jan 2019) to t2/t3 in August.

2020年11月3日 · I’m a 51 yo male and was diagnosed with CIS in the bladder hutch diverticulum. I was treated with an initial 1/3 dose (because of shortage) of BCG. Initial random biopsies showed NED. Repeat blue light cysto and random biopsies 3 mo. later showed CIS returned to diverticulum. Other biopsies on bladder itself show atypia but no cancer.

2023年5月27日 · A majority of patients with bladder cancer present with non-muscle invasive disease, and for patients with high-risk tumors, standard of care is resection of the tumor followed by intravesical BCG. Once patients experience recurrence and develop BCG-unresponsive disease, standard of care is radical cystectomy, which many patients are unfit for ...

2019年6月8日 · Cis (cis is a "flat" style of transitional cancer ) can be so diffuse ( wide spread out) it is not possible to to get it all. One cell left behind and back it grows again. Believe attempting to scrape the entire bladder would leave ones bladder a poor functioning inflamed mess.

2023年12月28日 · BCG is very effective for CIS as CIS is shallow and has not progressed through basal layer of the lining of the bladder. CIS cancer cells look high grade similar to cancer cells of T1HG under microscope, but CIS has not yet gained molecular characteristics to break through the basal layer of the lining of the bladder to reach the connective ...

2024年6月19日 · Your progression to CIS is a higher risk factor than your original presentation which adds to the treatment intensity. The pathway to a second opinion at a NCI is to first identify one most convenient to your location and then contact their nurse or patient navigators to book your initial appointment.

2015年9月11日 · Bladder washings can be obtained by placing a catheter into the bladder and vigorously irrigating with saline (ie, barbotage). Bladder wash cytology yields more tumor cells in the sample and is more sensitive in identifying cancer, especially for high-grade tumors, but it also yields a higher false-positive rate than voided urine cytology.[64]

2021年7月31日 · The false-positive rate is 1-12%, although cytology has a 95% accuracy rate for diagnosing high-grade carcinoma and CIS. Urine cytology is often the test used for diagnosis of CIS .Feb 23, 2021. The previous paragraph states that "95% accuracy rate for diagnosing high-grade carcinoma and CIS".