Growth differentiation factor 11 (GDF11), also known as bone morphogenetic protein 11 (BMP-11), is a protein that in humans is encoded by the growth differentiation factor 11 gene. [5] …

骨形态发生蛋白 11 (bmp-11; gdf11)，又称生长/分化因子 11，是一种多效配体蛋白，属于 tgfβ 家族。gdf-11/bmp-11 信号通过激活素受体 i 型、ii 型，导致 smad2 和 smad3 磷酸化，激发信 …

2023年6月1日 · Growth differentiation factor 11 (GDF11), also known BMP-11 (Bone morphogenic protein 11), was discovered in 1999 by Nakhashima et al. [7], who described …

Growth differentiation factor (GDF11) is a member of TGF-β/BMP superfamily that activates Smad and non-Smad signaling pathways and regulates expression of its target nuclear genes. …

1975年11月12日 · BMP-11/GDF-11 and Myostatin/GDF-8 are both members of the TGF-beta superfamily that can activate SMAD2/3 phosphorylation via the type I receptors ALK4, ALK5, …

2023年2月23日 · BMP-11 overexpression with an adenovirus was reported to alleviate cardiac ischemia‒reperfusion injury by enhancing mitochondrial biogenesis and telomerase activity in …

The single transmembrane domain serine/threonine kinase activin receptor type IIB (ActRIIB) has been proposed to bind key regulators of skeletal muscle mass development, including the …

GDF-11 (Growth Differentiation Factor 11), also known as BMP-11, is closely related to GDF-8. It is widely expressed during development and plays a role in palate, vertebrae, tail, kidney, and …

Growth Differentiation Factor 11 (GDF-11), also known as BMP-11, is a member of the TGF-beta superfamily and is highly related to GDF-8. GDF-11 encodes a 407 amino acid (aa) …

Growth Differentiation Factor 11 (GDF-11), also known as BMP-11, is a regulator of cell growth and differentiation during muscular and neural development. GDF-11 binds the Transforming …