2011年7月1日 · The basement membrane zone (BMZ) is a highly dynamic and complex structure that is important in the regulation of cell adhesion, differentiation, and motility; in the transmission of extracellular signals and growth factors; and in the formation of permeability barriers.

Granular IgM at the BMZ was found in three cases. C3 were also found at the BMZ with granular patterns (3 cases) and linear pattern (1 case). IgM deposition on the CB [ Table/Fig-7 ] was detected in more than half of the positive DIF cases followed in decreasing frequency by IgA, C3, and fibrinogen [ Table/Fig-5 ].

2015年1月1日 · The dermal-epidermal basement membrane zone (BMZ) is a complex, precisely organized, and dynamic collection of proteins which provide structure and regulate cell adhesion, differentiation, motility, signal transmission, and membrane permeability.

The reticular BMZ is the region of the BMZ that is visible in standard light microscope preparation and becomes thickened in asthma. It is commonly referred to as the reticular basement membrane. It consists of collagen types I, III, V, VI and VII collagen and three BMZ specific proteoglycans (perlecan, collagen XVIII and bamacan) ( 19 ).

A subset of patients with BP display deposition of IgE within the basement membrane zone (BMZ) of skin tissue. What does this study add? Patients with in vivo IgE deposition in the BMZ displayed higher erosion/blister Bullous Pemphigoid Disease Area Index (BPDAI) scores, while urticaria/erythema BPDAI scores were not significantly different.

Results: All the BMZ antigens found in the normal interfollicular epidermis were expressed in the anagen follicle; however, there were regional variations in the intensity and patterns of fluorescence. All the antigens were expressed in a continuous linear pattern along the BMZ of the interfollicular skin, the infundibulum, and the middle part ...

表皮基底膜带(BMZ)位于表皮与真皮之间。基底膜带很窄,仅50～90nm宽,可分为4层:①基底细胞浆膜:为与真皮相邻的基底细胞浆膜,其上有对表皮真皮连接起关键作用的半桥粒;②透明板:位于基底细胞浆膜的下方;③致密板;④致密板下带。

1994年3月1日 · Anchoring fibers are collagenous structures com- posed mainly of type VII collagen (1) and are found in the basement membrane zone (BMZ). They have been described in oral mucosa (2) and cervical ep- ithelium (3), but the majority of the investigations have concerned the characterization of anchoring fibers in skin (1,4-6).

The basement membrane zone (BMZ) is a highly dynamic and complex structure that is important in the regulation of cell adhesion, differentiation, and motility; in the transmission of extracellular signals and growth factors; and in the formation of permeability barriers.

1997年7月15日 · Skin basement membrane zone (BMZ) is an ultrastructurally defined area situated between the outer layer of skin, the epidermis, and the inner layer of skin, the dermis. The major function of skin BMZ is to serve as an adherent connection between the …