2016年2月16日 · In rodents, the BNST is a center for integration of information with negative valence or anxiety-like states due to the vastly studied role of corticotrophin-releasing factor (CRF) containing...

The bed nucleus of the stria terminalis (BNST) is a heterogeneous and complex limbic forebrain structure, which plays an important role in controlling autonomic, neuroendocrine and behavioral responses. The BNST is thought to serve as a key relay ...

2023年4月27日 · 本研究以野生型和PKC-δ-Cre的C57BL/6小鼠为研究对象，使用光遗传学和化学遗传学等多种实验技术， 发现椭圆部BNST（ovBNST）内的PKC-δ+神经元参与动物炎症引起的厌食症状，并对正常动物的摄食行为发挥双向调控作用。 ovBNST内的PKC-δ+神经元接受ARC、LPB和CEA等多个摄食相关脑区的传入调控，并对腹外侧BNST（vlBNST）内对摄食活动有重要作用的LH投射神经元的活动发挥抑制性调节作用。 结果显示，BNST内的PKC-δ+神经元群及相 …

2015年6月22日 · In this review, we will examine how stress interacts with the neuromodulators, corticotropin-releasing factor, norepinephrine, dopamine, and serotonin to affect the circuitry of the BNST as well...

2018年7月23日 · We characterized two non-overlapping LH-projecting GABAergic BNST subpopulations that express distinct neuropeptides (corticotropin-releasing factor, CRF, and cholecystokinin, CCK). To...

The bed nucleus of the stria terminalis (BNST) is a center of integration for limbic information and valence monitoring. The BNST, sometimes referred to as the extended amygdala, is located in the basal forebrain and is a sexually dimorphic structure made up of between 12 and 18 sub-nuclei.

Both, the anterior bed nucleus of the stria terminalis (BNST) and the neuropeptide Y (NPY) system are involved in shaping fear and defensive responses that adapt the organism to potentially life-threatening conditions. NPY is expressed in the BNST ...

To address this question, we recorded neurons in the anterolateral (AL) and anteromedial (AM) regions of BNST in rats subjected to auditory fear conditioning. During habituation, few neurons were responsive to the conditioned stimulus (CS). After fear conditioning, 20% of BNST-AL neurons developed inhibitory responses to the CS.

The bed nucleus of the stria terminalis (BNST) is a center of integration for limbic information and valence monitoring. The BNST, sometimes referred to as the extended amygdala, is located in the basal forebrain and is a sexually dimorphic ...

2014年1月1日 · The bed nucleus of the stria terminalis (BNST) is thought to generate anxiety-like states via its projections to autonomic and neuroendocrine regulatory structures of the brain. However, because most BNST cells are GABAergic, they are expected to inhibit target neurons.