2002年8月23日 · The TNF-like ligand BAFF/BLyS is a potent survival factor for B cells. It binds three receptors: TACI, BCMA, and BR3. We show that BR3 signaling promotes processing of …

2006年11月1日 · In order to investigate the consequences of targeting BR3 in murine models and to assess the potential of BR3 antibodies as human therapeutics, synthetic antibody phage …

2007年12月1日 · Based on the demonstrated synergy between B-cell depletion and blockade of B-cell survival through BR3, we developed anti-BR3 antibodies that combine, in one molecule, …

Antibody-neutralizing titers of BR3 plasma against TW1 viruses were similar to TW2 viruses. All time points refer to the twins infection; BR3 was infected with the twins' virus ∼13 mo later.

Antibody-neutralizing titers of TW1, TW2, and BR3 plasma against autologous and heterologous viruses.

BAFF Receptor (B-cell activating factor receptor, BAFF-R), also known as TNFRSF13C and BR3, is a membrane protein of the TNF receptor superfamily which recognizes BAFF. BAFF …

2007年12月1日 · Based on the demonstrated synergy between B-cell depletion and blockade of B-cell survival through BR3, we developed anti-BR3 antibodies that combine, in one molecule, …

2001年10月2日 · Here we report the identification of a third BLyS receptor (BR3; BLyS receptor 3). This receptor is unique in that, in contrast to TACI and BCMA, BR3 only binds BLyS. …

Inhibiting BAFF binding to BR3 or down-modulating BR3 expression augments CD25, IFN-γ, and granzyme B expression. In addition, our results demonstrate that BR3 blockade increases …

1992年5月1日 · Geometric enantiomerism in cyclic compounds: Chiral dibrominated 1,3-dioxanes.