BRF2 Gene - GeneCards | BRF2 Protein | BRF2 Antibody
2024年12月24日 · BRF2 (BRF2 General Transcription Factor IIIB Subunit) is a Protein Coding gene. Diseases associated with BRF2 include Prostate Cancer and Cone-Rod Dystrophy 9 . …
Redox Signaling by the RNA Polymerase III TFIIB-Related Factor Brf2
2015年12月3日 · TFIIB-related factor 2 (Brf2) is a member of the family of TFIIB-like core transcription factors. Brf2 recruits RNA polymerase (Pol) III to type III gene-external promoters, …
Redox Signaling by the RNA Polymerase III TFIIB-Related Factor Brf2
2015年12月3日 · Direct redox-sensing by the RNA polymerase III core transcription factor Brf2 couples cellular responses to oxidative stress and regulation of transcriptional output, …
BRF2 BRF2 general transcription factor IIIB subunit [ (human)]
2025年2月8日 · High expression of BRF2 is closely associated with tumor progression, angiogenesis, and poor survival in esophageal squamous cell cancer. BRF2 can serve as a …
Targeting BRF2 in Cancer Using Repurposed Drugs - PMC
2021年7月27日 · BRF2, a subunit of the RNA polymerase III transcription complex, is upregulated in a wide variety of cancers and is a potential therapeutic target; however, no effective drugs …
Redox Signaling by the RNA Polymerase III TFIIB-Related Factor Brf2
2015年12月3日 · Brf2 recruits RNA polymerase (Pol) III to type III gene-external promoters, including the U6 spliceosomal RNA and selenocysteine tRNA genes. Found only in …
RNA polymerase III transcription in cancer: the BRF2 connection
Recently, BRF2, a component of TFIIIB required for gene external RNA pol III transcription, was identified as an oncogene in squamous cell carcinomas of the lung through integrative …
A meta-analysis of BRF2 as a prognostic biomarker in invasive …
Deregulation of the RNA polymerase III specific TFIIIB subunit BRF2 occurs in subtypes of human cancers. However, correlations between BRF2 alterations and clinical outcomes in breast …
Targeting BRF2 in Cancer Using Repurposed Drugs - PubMed
2021年7月27日 · The overexpression of BRF2, a selective subunit of RNA polymerase III, has been shown to be crucial in the development of several types of cancers, including breast …
BRF2 RNA 聚合酶 III 转录起始因子亚基（BRF2）基因 | MCE
brf2 rna 聚合酶 iii 转录起始因子亚基： 该基因编码 rna 聚合酶 iii 转录因子复合物的多个亚基之一，该复合物是转录具有起始位点上游启动子元件的基因所必需的。