Expression of Bovine Viral Diarrhea Virus Glycoprotein E2 as a …
Bovine viral diarrhea virus (BVDV) membrane-anchored type I glycoprotein E2 is an ∼53-kDa immunodominant glycoprotein inducing the production of neutralizing antibodies in the animal …
CHO细胞表达牛病毒性腹泻病毒E2蛋白及免疫原性分析
摘要：旨在利用悬浮培养CHO细胞表达系统制备牛病毒性腹泻病毒 (bovine viral diarrhea virus, BVDV)E2蛋白，并鉴定纯化E2蛋白的免疫原性。 本研究以BVDV-1 NADL株基因序列为基 …
牛病毒性腹泻病毒蛋白的免疫学特性以及相关疫苗研究进展
基于bvdv e2蛋白在宿主免疫反应中的重要地位，系统研究基因突变对同义密码子使用模式以及蛋白结构域正确形成的影响、合理构建多表位e2抗原，对采用e2蛋白作为核心组件的bvdv基因 …
Frontiers | Recent Advances on the Bovine Viral Diarrhea Virus ...
2021年5月14日 · The BVDV-E2 protein plays important role in viral infection and pathogenesis. We mapped some important potential neutralizing epitopes among some BVDV genomes …
Formation of bovine viral diarrhea virus E1-E2 heterodimers is ... - PubMed
The envelope of bovine viral diarrhea virus (BVDV) contains the glycoproteins Erns, E1 and E2. Complementation of a recombinant vesicular stomatitis virus (VSV) with BVDV glycoproteins …
Immunogenicity of a secreted, C-terminally truncated, form of …
2023年1月6日 · Here, we report the development of a BVDV subunit vaccine by (i) the expression of a secreted form of a recombinant E2 glycoprotein using BHK21 cells and (ii) determination …
Polymorphic genetic characterization of E2 gene of bovine viral ...
2014年12月5日 · E2 glycoprotein is a major structural component of the BVDV virion and plays a key role in viral attachment to host cells and inducing immune responses against viral …
Evaluation of BVDV E2 proteins based on recombinant baculovirus ...
Bovine viral diarrhea virus (BVDV) is a significant immunosuppressive pathogen that has a major impact on the global cattle industry. Research efforts are currently focused on the envelope …
Polymorphic genetic characterization of E2 gene of bovine viral ...
2014年12月5日 · E2 glycoprotein is a major structural component of the BVDV virion and plays a key role in viral attachment to host cells and inducing immune responses against viral …
Presence of bovine viral diarrhea virus (BVDV) E2 glycoprotein in …
2000年8月10日 · The E2 glycoprotein of the bovine diarrhea disease virus (BVDV, genus Pestivirus), a major pathogen of cattle having world-wide economic impact, is the main target …