Silencing CA1 pyramidal cells output reveals the role of feedback ...
2024年3月11日 · Our data reveal that chronic silencing of CA1 pyramidal cell transmission robustly reduces feedback inhibition, leading to increases in the power, duration, and intrinsic …
Local activation of CA1 pyramidal cells induces theta-phase
2024年2月1日 · In CA1, an imposed excitation of PYRs was sufficient to generate precession. To investigate whether a rate increase combined with theta may suffice for synthetic precession, …
Theta oscillations represent collective dynamics of multineuronal ...
2023年4月12日 · Here, we simultaneously patch-clamp up to three CA1 pyramidal neurons in awake or anesthetized mice and find that the temporal evolution of the power and frequency of …
Local hippocampal fast gamma rhythms precede brain-wide ... - Nature
2018年12月18日 · a CA1 Hippocampal LFP trace (top) time-frequency spectrograms with four LFP envelopes (middle) and regional CBV dynamics (bottom) for a typical REM sleep episode. …
Theta oscillations as a substrate for medial prefrontal-hippocampal ...
Our results suggest that upregulated theta oscillatory firing of mPFC cells can signal transient interactions with specific CA1 assemblies, thus enabling distributed computations.
Inferring synaptic excitation/inhibition balance from field …
2017年9月1日 · Specifically, we show that LFP-PSD slope correlates with both anatomical E:I ratio—represented by changes in synaptic density ratio across CA1 layers—and dynamic E:I …
不同阿尔茨海默病小鼠海马 CA1 区的神经振荡紊乱,Current …
2023年9月6日 · 方法：在小鼠清醒静息阶段，通过植入微电极阵列记录海马CA1区的LFP。 Welch 快速傅立叶变换、连续小波变换和相位幅度耦合分析用于计算 LFP 中不同频段的功率密度和 …
自由行为在体钙成像应用 | 频率置乱揭示记忆机制奥秘？Nature子 …
研究团队通过注入表达GCaMP6fast的病毒载体到海马CA1区域，并借助Miniscope对自由活动的小鼠进行钙成像记录，成功记录了大量CA1主要细胞的活动。 实验中，他们设计了一个任务， …
Theta Phase Segregation of Input-Specific Gamma Patterns in Entorhinal ...
2014年10月22日 · We found that 30–80 Hz gamma dominated CA1 local field potentials (LFPs) on the descending phase of CA1 theta waves during navigation, with 60–120 Hz gamma at the …
Estimating Extracellular Spike Waveforms from CA1 Pyramidal
2013年12月31日 · We tested the method both on defined spike waveforms added to LFP recordings, and on in vivo-recorded extracellular spikes from hippocampal CA1 pyramidal cells …