Septal GABAergic inputs to CA1 govern contextual memory …
2020年10月30日 · To examine the function of the MS-CA1 pathway in memory retrieval, we first injected into the dorsal CA1 region a herpes simplex virus expressing yellow fluorescent …
Single excitatory axons form clustered synapses onto CA1 ... - Nature
2018年2月19日 · Here we show that single presynaptic axons form multiple, spatially clustered inputs onto the distal, but not proximal, dendrites of CA1 pyramidal neurons. These compound …
Topography and motion of acid-sensing ion channel intracellular domains
2021年7月22日 · Here, we describe the coarse topography of the chicken ASIC1 intracellular domains determined by fluorescence resonance energy transfer (FRET), measured using …
Optogenetic inhibition-mediated activity-dependent modification of CA1 ...
2020年10月5日 · In these rats, Halorhodopsin (NpHR-YFP, n = 4 rats) or Archaerhodopsin (ArchT, n = 1 rat) was expressed in the dorsal CA1 region of the hippocampus under the …
Silencing CA1 pyramidal cells output reveals the role of feedback ...
2024年3月11日 · Here we use conditional genetics to chronically silence CA1 pyramidal cell transmission, ablating the ability of these neurons to recruit feedback inhibition in the local …
An enhancer-AAV approach selectively targeting dentate granule …
2024年1月22日 · In addition, YFP expression was occasionally seen in putative CA1 pyramidal neurons. While this off-target effect does lessen the specificity of mscRE4 in granule cell …
Hippocampal CA1 Somatostatin Interneurons Originate in the …
2019年11月12日 · We previously showed that nearly 100% of hippocampal CA1 SST interneurons are labeled with YFP in Lhx6-Cre;R26R-YFP transgenic mice (Fogarty et al., …
Carbonic anhydrases, EPF2 and a novel protease mediate CO2 …
Our results identify mechanisms and genes that function in the repression of stomatal development in leaves during atmospheric CO 2 elevation, including the carbonic-anhydrase …
Cell-autonomous reduction of CYFIP2 is insufficient to induce …
2023年3月24日 · Fluorescence immunohistochemical analysis showed that CYFIP2 protein levels were selectively reduced in the hippocampal CA1, but not CA3, of 12-month-old Cyfip2 cKO …
Expression of channelrhodopsin-2 localized within the deep CA1 ...
2018年1月15日 · Our results demonstrate that expression in CA1 is specific to CBN negative, deep pyramidal cells. These findings highlight the utility of Thy1-ChR2-YFP, line 18, mice to …