Carbonic Anhydrase XII is a Clinically Significant, Molecular Tumor ...
We analyzed CAXII abundance on a collection of GSCs and functionally tested their response to exposure to CAXII blocking antibody 6A10. CA12 is highly expressed in glial tumors compared …
Carbonic anhydrase 12 - Wikipedia
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in various biological processes, including …
有救啦！肝癌最新治疗进展——CA12介导巨噬细胞的机制
2022年6月27日 · 通过比较从HCC患者的肿瘤和配对的非肿瘤肝组织中纯化的单核细胞差异表达的基因，该研究发现，在所有的αCA家族基因中，CA12是肿瘤浸润单核细胞中与非肿瘤肝组织 …
Carbonic Anhydrase XII Functions in Health and Disease - PMC
In brain tumors, an alternatively spliced form of CAXII is expressed. Higher expression of CAXII in breast cancer is indicative of lower grade disease. CAXII plays a key role in several …
CA12 Gene - GeneCards | CAH12 Protein | CAH12 Antibody
2024年12月24日 · CA12 (Carbonic Anhydrase 12) is a Protein Coding gene. Diseases associated with CA12 include Hyperchlorhidrosis, Isolated and Intracranial Hypertension, Idiopathic. …
CA12人源基因|CA12基因突变_致病性_靶点-RDDC官网
这个基因产物是一种I型膜蛋白，在正常组织如肾脏、结肠和胰腺中高度表达，并在10%的透明细胞肾癌中过表达。 已经在这个基因中鉴定出三种编码不同异型体的转录变异体。 [RefSeq,2014 …
Carbonic anhydrase XII expression is associated with histologic …
2010年11月1日 · To investigate whether expression of carbonic anhydrase XII (CA12) is associated with histologic grade of the tumors and radiotherapy outcomes of the patients with …
Carbonic Anhydrase 12 Protects Endplate Cartilage From …
2020年10月16日 · Among all the factors leading to IVDD, lumbar cartilage endplate (LCE) degeneration is considered a key factor. In the present study, we investigate the effect and …
Trafficking of carbonic anhydrase 12 and bicarbonate transporters …
Carbonic anhydrase 12 is considered an oncogenic and acidic microenvironmental factor in cancer cells. To verify the role of histamine signalling as an anti-cancer signal, we determined …
碳酸酐酶 XII 是胶质瘤中具有临床意义的分子肿瘤亚型特异性治疗 …
胶质母细胞瘤中的 ca12 表达与临床确定的 idh1 wt分子标记显着相关dna，who iv 级或没有 1p/19q 染色体臂共缺失。 此外，CA12 升高的肿瘤聚集成该疾病的间充质转录亚类。