Using in vivo extracellular unitary recordings of CA3 pyramidal hippocampal neurons, we compared the effect of SNF-8702, a potent selective CCKB receptor agonist, to that of CCK …

Here, we discover the crucial role of cholecystokinin (CCK) in heterosynaptic neuromodulation from the medial entorhinal cortex (MEC) to the hippocampus. Systematic knockout of the CCK …

1996年1月1日 · The interaction of sulfated cholecystokinin (CCK-8S) with excitatory amino acids (EAA) was studied on single units of the dorsal lateral geniculate nucleus (dlGN), the dentate …

Using in vivo extracellular unitary recordings of CA 3 pyramidal hippocampal neurons, we compared the effect of SNF-8702, a potent selective CCKB receptor agonist, to that of CCK …

The sulphated octapeptide C‐terminal fragment of cholecystokinin (CCK‐8s) is present in high concentration in the mammalian brain, where it acts via two types of receptor denoted CCKA, …

1.CCK的 神经生理学 简介 CCK是一种以不同形式存在的神经活性肽，以往曾经被认为是一种 肠肽，由33个氨基酸残基组成 多肽链，主要由十二指肠和空肠黏膜的细胞分泌，具有促进胆囊收 …

CCK excites neurons by binding two receptors, CCK 1 and CCK 2, expressed at low and high levels in the brain, respectively. Historically, CCK 2 receptors have been related to the …

2024年4月1日 · CCK facilitates hippocampal LTP by activating CCKBR, triggering MAPK pathways, and promoting AMPA trafficking. The hippocampus is a crucial brain region involved …

1995年9月1日 · In the present study, we performed field potential and whole cell recordings from the hippocampal CA3 region of M(2) receptor knockout mice to determine the role of M(2) …

The CCK-8S-induced Ca increases were blocked by the CCKB receptor antagonist PD135158 (100 nM) but not by the CCKA antagonist lorglumide (100 nM). We surmise that astrocytes …