2024年8月28日 · Cerebral amyloid angiopathy (CAA) is a cerebrovascular disorder caused by the accumulation of cerebral amyloid-β (Aβ) in the tunica media and adventitia of leptomeningeal and cortical vessels of the brain. The resultant vascular fragility tends to manifest in normotensive elderly patients as lobar intracerebral hemorrhage.

caa的主要影像标记物为脑叶出血、cmbs及css，t 2 * gre及swi序列能提高caa的检出率，临床上swi序列常用。年龄超过55岁，怀疑caa患者在常规ct及mri检查基础上，建议行swi检查，以期早期诊断，降低患者病残率和病死率。

Cerebral amyloid angiopathy-related inflammation (CAA-RI) is a rare but increasingly recognized subtype of CAA. CAA-RI consists of two subtypes: inflammatory cerebral amyloid angiopathy and amyloid β (Aβ)-related angiitis. Acute or subacute onset of ...

脑淀粉样血管病（cerebral amyloid angiopathy，CAA）是指淀粉样蛋白β（amyloid β，Aβ）在脑膜和皮质小血管壁内的沉积，主要见于小动脉和毛细血管，偶可发生于小静脉。

2018年1月15日 · Patterns of cortical superficial siderosis (cSS) in patients with cerebral amyloid angiopathy (CAA). A, Susceptibility-weighted imaging (SWI) magnetic resonance imaging (MRI) showing a single sulcus with cSS (arrow), classified as focal cSS.

Local deposition of Aʲ into small to medium vessels of CNS and leptomeninges can lead to cerebral amyloid angiopathy (CAA), which is an untreatable disease mostly of the older population known for lobar cerebral hemorrhages and cognitive decline [2].

脑微出血（CMBs）是脑小血管病的典型影像学表现之一，常见于高血压性动脉病和脑淀粉样血管病（Cerebral amyloid angiopathy , CAA）患者。 然而，CMBs还可以出现在一些脑小…

2016年12月12日 · 淀粉样脑血管病(caa)以脑内小血管壁的β-淀粉样蛋白沉积为特征，是症状性颅内出血和无症状性脑内微出血（cmbs）的主要病因。 近年来，皮质表面铁沉积（cSS）受到广泛关注，其以含铁血黄素沿软脑膜下区域和脑回的线状沉积为特点。

We applied a new imaging method, susceptibility weighted imaging (SWI), to evaluate the presence of microhemorrhages. In a suspected case of CAA, where cognitive effects are also present, we show that SWI is much more sensitive in detecting microhemorrhages than conventional methods.

SUMMARY: Gradient-echo (GE) imaging is recognized as a means to detect hemorrhagic changes in cerebral amyloid angiopathy (CAA). However, almost 25% of patients with CAA do not show micro-hemorrhages on T2* GE imaging. We applied a new imaging method, susceptibility weighted imaging (SWI), to evaluate the presence of microhemorrhages.