CCNE1 Gene - GeneCards | CCNE1 Protein | CCNE1 Antibody
2024年12月24日 · CCNE1 (Cyclin E1) is a Protein Coding gene. Diseases associated with CCNE1 include Pancreatic Cancer and Ovarian Cancer. Among its related pathways are …
Cyclin E1 - Wikipedia
G1/S-specific cyclin-E1 is a protein that in humans is encoded by the CCNE1 gene. [5] The protein encoded by this gene belongs to the highly conserved cyclin family, whose members …
CCNE1 amplification is synthetic lethal with PKMYT1 kinase …
2022年4月20日 · To uncover therapeutic targets for tumours with CCNE1 amplification, we undertook genome-scale CRISPR–Cas9-based synthetic lethality screens in cellular models of …
细胞周期蛋白 E1（CCNE1）基因 | MCE - MCE-生物活性分子大师
由该基因编码的蛋白质属于高度保守的细胞周期蛋白家族，其成员的特点是在整个细胞周期中蛋白质丰度具有显着的周期性。 细胞周期蛋白作为 CDK 激酶的调节剂发挥作用。 不同的细胞周 …
CCNE1 copy number is a biomarker for response to ... - Cell Press
These studies demonstrate that CCNE1 CN is a clinically tractable biomarker predicting responsiveness to low-dose WEE1i-ATRi for aggressive subsets of OVCAs/EMCAs. …
新靶点 新希望 | CCNE1扩增作为治疗靶点的前景 - 网易
2023年2月16日 · 细胞周期蛋白E1 (CCNE1)是细胞周期由G1期向S期转变的关键调节因子，它能够激活细胞周期蛋白依赖性激酶2（CDK2）， 使其进入S期并促进DNA复制。 CCNE1的过度表 …
898 - Gene ResultCCNE1 cyclin E1 [ (human)] - National Center for ...
2025年2月9日 · CCNE1 Is a Putative Therapeutic Target for ARID1A-Mutated Ovarian Clear Cell Carcinoma. Cyclin E1 expression and malignancy in meningiomas. Reduced RBX1 expression …
CCNE1 is a predictive and immunotherapeutic indicator in various ...
2023年3月24日 · Our study demonstrated that CCNE1 is upregulated in multiple cancers in the TCGA database and may be a promising predictive biomarker for the immunotherapy …
CCNE1 Amplification as a Predictive Biomarker of Chemotherapy ...
2020年5月5日 · CCNE1 amplification has been identified as a primary oncogenic driver in a subset of high grade serous ovarian cancer that have an unmet clinical need. Understanding …
细胞周期蛋白E1与恶性肿瘤关系的研究进展
摘要： 细胞周期蛋白E1（Cyclin E1），是由CCNE1基因编码的一种核蛋白，在细胞周期中表现为循环式的表达，在整个细胞周期进程中发挥至关重要的作用。该蛋白通过激活细胞周期蛋白依 …