CCR7 is a chemokine receptor for the chemokines CCL19 (CKbeta11, ELC, MIP3beta, Scya19, Exodus-3) and CCL21 (CKbeta9, SLC, MIP2beta, Scya21, Exodus-2). In addition to its …

2018年6月15日 · Detection of CCR7 on Human Peripheral Blood Cells. Human whole blood was stained with Mouse anti-Human CCR7 APC-conjugated Monoclonal Antibody (Catalog # …

2023年9月1日 · Upon exposure to the CCR7 ligand CCL19, dendritic cells (DCs) effectively internalize the receptor and ligand as part of the canonical GPCR desensitization response. …

For many CCR stainings (like CCR7, eg) we stain at 37C for 10-15 minutes, then shift to RT and add the remaining antibodies for another 15 min. We rarely stain on ice anymore. Even for...

Moreover, we show that CCL19-S6 Dy649P1 serves as powerful reagent to monitor CCR7 internalization by time-lapse confocal video microscopy and to stain CCR7-positive primary …

2019年10月22日 · Here, we uncover a function for an intracellular pool of the chemokine receptor CCR7 present in human dendritic cells and cellular model systems. We find that CCR7 …

We demonstrate that CCR7 triggering alone is sufficient to recruit and activate ZAP70, a critical kinase for T cell activation, through Src kinase, whereas TCR CCR7 co-stimulation results in …

I am using PE and conjugates for staining of membrane extracellular proteins (CCR7, CXCR3, CD45RO), and I should stain for them after permeabilization, intracellular Mab addition and …

2024年9月9日 · As discussed last week, human CCR7 staining is highly dependent on temperature during the incubation. Today we'll look at the behaviour of three different clones- …

2025年3月1日 · In cancers, CCR7 has been revealed as a critical molecule in lymph node metastasis. Consequently, anti-CCR7 monoclonal antibodies (mAbs) have been developed as …