"Cd105" redirects here. For the isotope of cadmium (Cd-105 or 105 Cd), see Cadmium-105.

2024年5月11日 · CD105是一种血管内皮糖蛋白，它在血管生成，炎症反应，免疫应答中起着重要的作用，其中CD105的表达与肿瘤的血管生成和转移有关，它是血管疾病的标志物，是血管疾病和一些癌症的治疗靶点。

Substances Antigens, CD ENG protein, human Endoglin Receptors, Cell Surface Transforming Growth Factor beta

Endoglin (CD105) is an accessory receptor for transforming growth factor beta (TGF-β) and its expression is up-regulated in actively proliferating endothelial cells. Endoglin has been suggested as an appropriate marker for tumor-related angiogenesis …

Additionally, endoglin is associated with the spheroidization ability of cells and plays an active role in the invasive abilities of carcinoma cells [105]. The possibility of targeting CD105 in pancreatic cancer cells has been demonstrated using photochemical internalization transfection (PCI).

CD105 Is a Surface Marker for Receptor-Targeted Gene Transfer into Human Long-Term Repopulating Hematopoietic Stem Cells

2003年10月3日 · Among surface molecules expressed on endothelial cells, endoglin (CD105) is emerging as a prime vascular target for antiangiogenetic cancer therapy. CD105 is a cell membrane glycoprotein mainly ...

2019年12月4日 · Generation of a novel CD105 antibody The murine CD105 IgG2b antibody K-ro23 was generated as described in Methods section. SDS-PAGE analyses and size exclusion chromatography confirmed the ...

Abstract Endoglin (CD105) is a component of the transforming growth factor-beta (TGF-beta) receptor (TGF-betaR) complex. Together with betaglycan, CD105 is considered as a TGF-betaR accessory molecule (also called TGF-betaRIII), but its functions in the receptor-ligand interactions are still poorly understood. A small subset of human CD34+ hematopoietic stem/progenitor cells …

摘要： CD105是一个特异表达于新生血管内皮的糖蛋白,主要标记具有增殖活性的内皮细胞.肿瘤生长和浸润有赖于血管生成,新生的血管提供给肿瘤组织营养及氧分.为肿瘤组织增殖提供了基础.CD105是肿瘤新生血管的标志物,其标记的微血管密度,优于其他标志物,更能反映肿瘤的增殖状态和预后,血管生成是 ...