CD22 - Wikipedia
CD22 is a sugar binding transmembrane protein, which specifically binds sialic acid with an immunoglobulin (Ig) domain located at its N-terminus. The presence of Ig domains makes …
Targeting CD22 for the Treatment of B-Cell Malignancies - PMC
2021年7月21日 · CD22 presents an attractive target in lymphoid neoplasms given its unique presence in B-lymphocytes. Due to its role in regulating B-cell function, CD22 has also been …
CD22 - an overview | ScienceDirect Topics
CD22 is a transmembrane molecule that acts as a molecular switch to inhibit signaling by the B-cell receptor, leading to apoptosis instead of proliferation in stimulated B cells. It is strongly …
CD22 - 维基百科，自由的百科全书
CD22是一种可高度特异性识别糖基化蛋白（如 CD45）的 跨膜蛋白，可通过 N端 的一个 免疫球蛋白（Ig）结构域 （英语：immunoglobulin domain） 與 唾液酸 結合。 因擁有Ig结构 …
肿瘤免疫靶点 | CD22 - 知乎 - 知乎专栏
CD22 (Siglec-2）属于唾液酸结合免疫球蛋白型凝集素家族（Siglecs）成员，是一种I型跨膜蛋白，可特异性结合含唾液酸（Sia）的聚糖，并通过其免疫受体酪氨酸抑制性基序（ITIM）抑制B …
CD22 Gene - GeneCards | CD22 Protein | CD22 Antibody
2024年12月24日 · CD22 (CD22 Molecule) is a Protein Coding gene. Diseases associated with CD22 include Hematologic Cancer and Trichomoniasis. Among its related pathways are …
CD22: an inhibitory enigma - PMC - National Center for …
CD22 is an inhibitory coreceptor of the B-cell receptor (BCR) and, like other coreceptors, is required to modulate the antigen receptor signal in response to cues from the local …
CD22 protein expression summary - The Human Protein Atlas
High and selective cytoplasmic expression in subsets of lymphocytes. Main subcellular location based on data generated in the subcellular section of the Human Protein Atlas. All transcripts …
CD22——自身免疫疾病和B细胞恶性肿瘤治疗的热门靶点之一 - 每 …
2020年12月22日 · CD22限制性地表达于成熟B细胞和大多数恶性B淋巴瘤细胞表面，使其成为了自身免疫疾病和B细胞恶性肿瘤治疗的热门靶点之一，目前，以CD22为靶点的免疫治疗药物种 …
Frontiers | CD22: A Regulator of Innate and Adaptive B Cell …
2018年9月27日 · CD22 (Siglec 2) is a receptor predominantly restricted to B cells. It was initially characterized over 30 years ago and named “CD22” in 1984 at the 2nd International workshop …