2021年2月19日 · 这项研究发现了 恶性脑肿瘤免疫治疗的一个潜在新靶点——cd161。目前的研究显示，cd161作为一种抑制免疫t细胞抗癌活动的分子，一直在抵抗基于人体免疫系统的突破性 …

Killer cell lectin-like receptor subfamily B, member 1, also known as KLRB1, NKR-P1A or CD161 (cluster of differentiation 161), is a human gene. [5] Natural killer (NK) cells are lymphocytes …

对克隆扩增肿瘤浸润T细胞的分析进一步确定NK基因KLRB1 (编码CD161)为候选抑制受体。 因此，KLRB1基因失活或抗体介导的CD161阻断剂增强了T细胞介导的胶质瘤细胞体外杀伤和体内 …

2015年7月29日 · The C-type lectin-like receptor CD161 is expressed by lymphocytes found in human gut and liver, as well as blood, especially natural killer (NK) cells, T helper 17 (Th17) …

CD161，别名NKRP1A（NK受体P1A）、KLRB1、CLEC5D，以下均称为CD161。其中，KLRB1（killer cell lectin-like receptor subfamily B1）是推荐的名称，中文翻译为“杀伤细胞的 …

High levels of CD4+CD161+ Tem are associated with improved survival and our data show that CD161 is dynamically regulated by cell intrinsic and extrinsic factors. CD161 expressing CD4+ …

2014年11月6日 · T lymphocytes are conventionally divided into subsets based on expression of coreceptors, cytokines, and surface molecules. Using CyTOF and mRNA microarray analysis, …

2018年4月8日 · CD161 is a C-type lectin-like receptor expressed on the majority of natural killer (NK) cells; however, the significance of CD161 expression on NK cells has not been …

Expression of killer cell lectin-like receptor B1 (KLRB1), the gene encoding the cell surface molecule CD161, is associated with favorable prognosis in many cancers. CD161 is …

Human C-type lectin-like CD161 is a type-II transmembrane protein expressed on the surface of various lymphocytes across innate and adaptive immune systems. CD161+ T cells displayed …