We show that CD200 is uniformly expressed in chronic lymphocytic leukemia (CLL) and absent in mantle cell lymphoma (MCL). Importantly, expression of CD200 is retained even in those CLLs …

2024年12月24日 · CD200 (CD200 Molecule) is a Protein Coding gene. Diseases associated with CD200 include Hairy Cell Leukemia and Indian Tick Typhus. Among its related pathways are …

CD200 is a new marker that was found to be up-regulated in chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma (SLL) when compared with normal B cells by flow …

Through this CD200/CD200R signaling pathway, CD200 exerts its immunosuppressive effects by inhibiting natural killer (NK) cell activation, cytotoxic T cell functions, and M1-polarized …

2021年5月12日 · Our data show that the CD200-CD200R pathway restrains activation of CD200R+ lesional macrophages, their production of CCR2 ligands, and monocyte recruitment …

CD200 is a transmembrane protein related to the B7 family of costimulatory receptors involved in T-cell signaling and likely plays a role in physiologic immune tolerance. It is normally …

2020年11月25日 · CD200, a transmembrane type Ia glycoprotein belonging to the immunoglobulin protein superfamily, is broadly expressed on a wide variety of cell types, such …

2020年11月26日 · In this review, we focus on the role of CD200 expression in the differential diagnosis of mature B-cell neoplasms and on the prognostic significance of CD200 expression …

2024年2月23日 · CD200 + DKK3 + fibroblasts stabilized the type 2 innate lymphoid cell phenotype and induced resolution of arthritis via CD200–CD200R1 signaling. Taken together, …

2014年12月6日 · The present study aimed to prove CD200 usefulness in differentiating CLL from MCL on a series of consecutive patients and to investigate whether adding CD200 could …