CD303 is another specific surface marker of human pDCs, centrally involved in antigen presentation and immune tolerance. Monoclonal antibodies directed against CD303 have been …

BDCA-2靶点全名为血液树突状细胞抗原2也叫CLEC4C或CD303，是在浆细胞样树突状细胞（PDC）上的唯一表达，是一种II型c型凝集素。 BDCA-2结构. 与BCR信号转导类似，BDCA …

cd303. clec4c、bcda-2. 浆细胞样树突细胞和源自单核细胞的未成熟树突细胞。 捕获抗原并将肽送入用于呈递给 t 细胞的细胞室，可能介导浆细胞样树突细胞中 ifn-α/β 表达诱导的抑制。同时 …

2013年7月11日 · BDCA-2 is a type II C-type lectin receptor selectively expressed on PDCs, where it is involved in antigen capture and in regulation of the production of interferon type I. Dzionek …

1 天前 · Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare and aggressive hematologic malignancy characterized by the overexpression of CD123 and CD303 surface …

The CD303 (BDCA-2) antigen is a novel type II transmembrane C-type lectin. 3 Remarkably, plasmacytoid dendritic cells can take up ligands via CD303 (BDCA-2), then process and …

CD303 is another specific surface marker of human pDCs, centrally involved in antigen presentation and immune tolerance. Monoclonal antibodies directed against CD303 have been …

CD303 (BDCA-2) is a type II c-type lectin specifically expressed by human PDC. CD303 signaling induces tyrosine phosphorylation and Src kinase dependent calcium influx. Cross-linking …

We are proposing here, as a new targeted-based therapy, a novel chimeric monoclonal antibody (mAb) that mediates a strong cellular cytotoxicity directed against a specific human pDC …

CD303 (BDCA-2) is a highly specific marker for normal and neoplastic plasmacytoid dendritic cells and may be useful as a specific marker for the diagnosis of blastic plasmacytoid dendritic cell …