1997年9月15日 · We have identified seven cases of a unique form of acute leukemia of conceivable myeloid/NK cell precursor phenotype (ie, CD7 +, CD33 +, CD34 +, CD56 +, and frequently HLA-DR + type) suggested to be immature in terms of morphology, phenotype, and genotype compared with those described by Scott et al. 14 These seven cases were all characterized ...

2009年11月26日 · Our data indicate that CD7 and CD56 coexpression discriminates NK cells from CD7 neg CD56 + monocyte/DC-like cells, thereby improving our ability to study the intricacies of NK-cell subset phenotypes and functions in vivo.

Our data showed that CD7 and CD56 positivity at diagnosis associated with low remission rate and biological aggressiveness in a significant proportion of patients. We suggest the evaluation of CD7 and CD56 in all patients with acute leukaemias at the time of diagnosis in view of poor clinical outcome.

2020年6月19日 · 查阅近年来相关文献，现就 CD 7、CD19、CD56 抗原. 在急性髓系白血病方面是否有独特临床特征、遗传标志及预后方面的信息进行阐述。 热、肝脾淋巴结肿大 、骨骼疼痛等各器官浸润症状。 AML 、伴骨髓增生异常综合征（MDS）病史。 其中，细胞. 性髓系白血病重要的独立预后因素之一。 有文献报道 [，急. 缺乏特征性的染色体变化， 然而这部分预后差异明显。 另 …

2024年11月5日 · The immunophenotypic markers CD7 and CD56 identify patients with adverse outcomes following HMA+VEN therapy independent of mPRS risk group, additional genetic mutations, and underlying cytogenetics.

对于AML患者，首先观察髓系标志抗原强度是否异常，及是否出现早期和晚期标志共表达，还应检测是否表达淋系标志，如CD7、CD56、CD19等。 其他标志如CD5、CD2表达比例相对低，可选择性应用。

1997年9月15日 · These data suggested that the CD7+ and CD56+ myeloid/NK cell precursor acute leukemia might constitute a distinct biologic and clinical disease entity. Its recognition appears to be particularly important for the clinicopathologic evaluation of CD56+ hematolymphoid malignancies and the development of therapeutic approaches to such disease.

2024年12月12日 · These results indicate that CD56 − CD7 + CD34 − HLA-DR − lineage marker (Lin) − cells are the major origin of human CB-derived CAR-NK cells, indicating the importance of developing methods to enhance the quality and quantity of …

2009年11月26日 · Our data indicate that CD7 and CD56 coexpression discriminates NK cells from CD7 (neg)CD56+ monocyte/DC-like cells, thereby improving our ability to study the intricacies of NK-cell subset phenotypes and functions in vivo.

CD16和CD56是两种最常用于定义NK细胞的抗原。 NK细胞上的CD16与早先在粒细胞上描述的细胞外分子相同，但它是完全跨膜的并且具有ITAM的细胞质尾部而不是通过GPI锚附着。