CD68 (Cluster of Differentiation 68) is a protein highly expressed by cells in the monocyte lineage (e.g., monocytic phagocytes, osteoclasts), by circulating macrophages, and by tissue macrophages (e.g., Kupffer cells, microglia).

2024年12月24日 · CD68 (CD68 Molecule) is a Protein Coding gene. Diseases associated with CD68 include Granular Cell Tumor and Histiocytic Sarcoma. Among its related pathways are Innate Immune System and Macrophage markers. An important paralog of this gene is LAMP1.

CD68 is a valuable marker which can be used to identify macrophages and monocytes, and also has implications in the diagnosis of various disease conditions.

2014年2月24日 · CD68 is a type I transmembrane glycoprotein present in macrophages and monocytes and CD68 antibodies may be used to distinguish between Crohn’s Disease and Chronic Granulomatous Disease. Read the Blog!

CD68 is a specialized type of protein highly expressed in cells of the monocyte-macrophage lineage. It serves as a marker for these cells in various tissues and is involved in the immune system’s response to pathogens and the clearance of cellular debris.

2025年2月7日 · CD68 positive cells, primarily macrophages, have garnered attention for their role in cancer prognosis due to their involvement in tumor immune responses and impact on disease outcomes. Understanding these cells is crucial for insights …

2025年2月8日 · CD68, a transmembrane glycoprotein, is predominantly expressed on macrophages and serves as a reliable marker for these immune cells. Its structure, characterized by a heavily glycosylated extracellular domain, facilitates its role in …

2024年11月5日 · CD68 is a macrophage marker, expressed in LAMs, with a role in clearing cell debris, regulating phagocytosis, and recruiting macrophages. CD68 has also been proposed as a universal monitoring marker of minimal residual disease (MRD) in adult AML and is the most commonly expressed marker in myeloid sarcoma.

CD68 is a transmembrane glycoprotein that is highly expressed in monocytes and macrophages. Although it is lowly expressed in hematopoietic cell lines, CD68 can be induced by PMA/TPA. It can bind to tissue and organ-specific lectins or selectins, allowing macrophage subpopulations to home to specific sites.

a type I transmembrane protein present on monocytes, macrophages, osteoclasts, mast cells, cytoplasmic granules, activated platelets, and large lymphocytes; expressed in neuroma Schwann cells, in nerves undergoing wallerian degeneration, in myeloid cell tumors, and in anaplastic lymphomas and epithelial tumors. Want to thank TFD for its existence?