Cluster of Differentiation 86 (also known as CD86 and B7-2) is a protein constitutively expressed on dendritic cells, Langerhans cells, macrophages, B-cells (including memory B-cells), and on …

目前免疫学家们分离出了很多种不同的共刺激分子，其中研究最清楚的一种是表达在抗原呈递细胞（apc）表面的b7家族蛋白，即cd80（b7-1）和cd86（b7-2）蛋白。

CD80/CD86是最早发现的B7家族成员，基因分别定位于人类染色体的3q13.3~q21和3q21区，两者有25％的氨基酸同源，胞外结构域均为IgV+IgC。 CD86主要以较低水平表达于抗原呈递细 …

Cluster of differentiation 86 (CD86), also known as B7-2, is a molecule expressed on antigen-presenting cells that provides the costimulatory signals required for T cell activation and …

1998年2月15日 · Data accumulated to date suggest that the interaction between CD28 expressed on T cells and its counter-receptors CD80 (B7-1) and CD86 (B7-2) expressed on specialized …

B7-0 or B7-2 (CD86) is a T cell costimulatory molecule that binds the same receptors (CD28 and CTLA-4) as B7-1 (CD80), but shares with it only approximately 25% sequence identity and is …

The ligands or counterreceptors for these two proteins are the B7 family members, CD80 (B7-1) and CD86 (B7-2). This article reviews the CD28/CTLA4 and CD80/CD86 families, and outlines …

Recent studies demonstrated the existence of at least two ligands on accessory cells, CD80 (B7-1) and CD86 (B7-2). In this study we demonstrate that, although CD80 and CD86 are both …

1997年6月20日 · The CD28 ligands, CD80 (B7-1) and CD86 (B7-2), are expressed on human tonsillar B cells, and their expression is up-regulated by IL-4, IL-13, and/or an anti-CD40 …

即cd86。 属B7家族成员，主要表达于某些抗原提呈细胞表面，能与CD28结合，可提供T细胞活化的协同刺激信号，与细胞毒性T淋巴细胞抗原4(CTLA-4)结合，可启动抑制性信号，对T细胞活 …