
CEACAM5 Gene - GeneCards | CEAM5 Protein | CEAM5 Antibody
Mar 30, 2025 · CEACAM5 (CEA Cell Adhesion Molecule 5) is a Protein Coding gene. Diseases associated with CEACAM5 include Lung Non-Small Cell Carcinoma and Bile Duct Cancer. Among its related pathways are Metabolism of proteins and Response to elevated platelet cytosolic Ca2+.
A novel human single-domain antibody-drug conjugate targeting CEACAM5 …
Nov 29, 2023 · Carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) is a glycosylated cell surface protein that rarely expressed in normal adult tissues but overexpressed in diverse...
Identification of CEACAM5 as a Biomarker for Prewarning and …
Here we identified that the antigen of MGd1 is CEACAM5, and used MGd1 to investigate the expression of CEACAM5 in non-GC and GC tissues (N=643), as a biomarker for prewarning and prognosis.
Detection and clinical significance of CEACAM5 methylation in ...
Patients with hypermethylation of the CEACAM5 promoter showed features of a BRAF mutation, TGFB2 mutation, microsatellite instability‐high, and preference for right‐sided colorectal cancer and peritoneal seeding presentation that had a similar clinical character to the consensus molecular subtype 1 (CMS1) of colorectal cancer.
CEACAM5 stimulates the progression of non-small-cell lung …
To detect the expression of CEA-related cell adhesion molecule 5 (CEACAM5) in non-small-cell lung cancer (NSCLC) and explore its function in the progression and development of NSCLC. qRT-PCR and immunohistochemistry were performed to detect CEACAM5 expression in human NSCLC tissues and cell lines.
CEACAM5 CEA cell adhesion molecule 5 [ (human)]
CEACAM5 overexpression is a reliable characteristic of CD133-positive colorectal cancer stem cells. A novel model for extrapleural cavity metastasis assessment in patients with lung cancer.
CEACAM5, an emerging target for cancer therapy
Sep 19, 2023 · Human carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5), initially discovered in colon cancer by Gold and Freeman in 1965 [1] [2], has long served as a pivotal tumor marker for clinical detection and diagnosis of colorectal cancer.
CEACAM5 CEA cell adhesion molecule 5 [Homo sapiens …
Jan 4, 2025 · Differential expression of carcinoembryonic antigen-related cell adhesion molecule-5 (CEACAM5) and dipeptidyl peptidase-4 (DPP4) with detection of Middle East respiratory syndrome-coronavirus in peripheral blood.
CEACAM5 stimulates the progression of non-small-cell lung …
Objective: To detect the expression of CEA-related cell adhesion molecule 5 (CEACAM5) in non-small-cell lung cancer (NSCLC) and explore its function in the progression and development of NSCLC. Methods: qRT-PCR and immunohistochemistry were performed to detect CEACAM5 expression in human NSCLC tissues and cell lines.
Assessment of carcinoembryonic antigen-related cell adhesion …
May 29, 2024 · Background: Carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) is an emerging target of antibody-drug conjugate therapy for non-small cell lung cancer (NSCLC). High expression of CEACAM5 has been reported in approximately 25% of patients with lung adenocarcinoma (Lefebvre AM, et al. Lung Cancer. 2023; 184:107356).
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