CENPA Gene - GeneCards | CENPA Protein | CENPA Antibody
2024年12月24日 · CENPA (Centromere Protein A) is a Protein Coding gene. Diseases associated with CENPA include Crest Syndrome and Luminal Breast Carcinoma A. Among its related …
CENPA - Wikipedia
Centromere protein A, also known as CENPA, is a protein which in humans is encoded by the CENPA gene. [5] CENPA is a histone H3 variant which is the critical factor determining the …
着丝粒蛋白 A（CENPA）基因 | MCE - MCE-生物活性分子大师
Centromere protein A is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 …
Center for Experimental Nuclear Physics and Astrophysics (CENPA ...
Physics New Grad BBQ at CENPA - Sept 18th, 2024. Brynn Kristen MacCoy receives 2024 URA Honorary Doctoral Thesis Award. 2023 Annual Report. CENPA Group Photo 2023. 2022 …
CENP-A: A Histone H3 Variant with Key Roles in Centromere
Focusing on the mammalian centromere- specific histone H3 variant, CENP-A, we highlight its coevolution with both centromeric DNA and its chaperone, HJURP. We then consider CENP-A …
生命科学学院刘君课题组与合作者揭示m6A-cenRNA调控癌细胞着 …
2024年10月9日 · cenpa在传统上被认为是着丝粒特异性组蛋白。 本研究发现CENPA通过与m 6 A-cenRNA的互作，在RNA表观遗传层面直接调控癌细胞中着丝粒完整性。 这提出了RNA表观 …
CENP-A overexpression promotes distinct fates in human cells …
2021年3月26日 · CENP-A, the centromeric histone H3 variant, is an epigenetic mark that directly perturbs genetic stability and chromatin when overexpressed. Although CENP-A …
m6A-modified cenRNA stabilizes CENPA to ensure centromere …
2024年9月20日 · Here, we discovered elevated levels of m 6 A modification on centromeric RNA (cenRNA) in cancerous cells compared with non-cancerous cells. We then identified CENPA, …
m6A修饰的cenRNA稳定CENPA以调控癌细胞着丝粒稳态_澎湃号· …
2024年9月25日 · CENPA is localized at centromeres and is essential in preserving centromere integrity and function during mitosis. The m6A-modified cenRNA stabilizes centromeric …
CENPA functions as a transcriptional regulator to promote ...
2023年10月16日 · The centromere proteins (CENPs), a critical mitosis-related protein complexes, are involved in the kinetochore assembly and chromosome segregation. In this study, we …