CHD4 - Wikipedia
Chromodomain-helicase-DNA-binding protein 4 is an enzyme that in humans is encoded by the CHD4 gene. [5][6][7] CHD4 is the core nucleosome-remodelling component of the …
CHD4 Gene - GeneCards | CHD4 Protein | CHD4 Antibody
2024年12月24日 · CHD4 (Chromodomain Helicase DNA Binding Protein 4) is a Protein Coding gene. Diseases associated with CHD4 include Sifrim-Hitz-Weiss Syndrome and Pallister-Hall …
CHD4 Neurodevelopmental Disorder - GeneReviews® - NCBI Bookshelf
2020年9月3日 · CHD4 neurodevelopmental disorder (CHD4-NDD) is associated with developmental delay, speech delay, and usually mild-to-moderate intellectual disability. …
色域解旋酶 DNA 结合 4 (CHD4) 调节早期 B 细胞身份 ... - X-MOL
CHD4是Nucleosome Remodeling和去乙酰化酶或NuRD (Mi-2) 复合物，与其他介导转录抑制的蛋白质组装。 我们回顾了证明 CHD4 对 B 谱系识别是必需的数据：早期 B 谱系进展、对白细胞 …
染色体解旋酶 DNA 结合蛋白 4（CHD4）基因 | MCE
该基因的产物属于 SNF2/RAD54 解旋酶家族。 它是核小体重塑和脱乙酰酶复合物的主要成分，在表观遗传转录抑制中起重要作用。 皮肌炎患者会产生针对这种蛋白质的抗体。 该基因的体细 …
The CHD4-related syndrome: a comprehensive investigation of …
2019年8月7日 · The CHD4-related syndrome is a multisystemic neurodevelopmental disorder. Missense substitutions in different protein domains alter CHD4 function in a variant-specific …
染色质重塑因子 CHD4 对 DNA 损伤反应和细胞周期进程的调节 …
We show that CHD4 mediates rapid poly (ADP-ribose)-dependent recruitment of the NuRD complex to DNA-damage sites, and we identify CHD4 as a phosphorylation target for the …
The role of auxiliary domains in modulating CHD4 activity …
2022年12月6日 · CHD4 is an essential, widely conserved ATP-dependent translocase that is also a broad tumour dependency. In common with other SF2-family chromatin remodelling …
CHD4 chromodomain helicase DNA binding protein 4 [ (human)]
CHD4 mediates proliferation and migration of non-small cell lung cancer via the RhoA/ROCK pathway by regulating PHF5A. Chd4 choreographs self-antigen expression for central immune …
The chromatin remodeling enzyme Chd4 regulates genome
2020年7月9日 · Here, we report that conditional knockout of the chromatin remodeling enzyme Chd4 in granule neurons of the mouse cerebellum increases accessibility of gene regulatory …