2007年12月10日 · TIA-1 or TIAR KO MEFs were infected with a retroviral construct expressing CIRP in fusion with the Flag epitope. After selection, cells were treated or not with arsenite to …

2020年9月24日 · 冷诱导RNA结合蛋白（cold inducible RNA-binding protein, CIRP）是一种RNA结合蛋白，属于冷休克蛋白家族，广泛表达于各种组织细胞中, 且在冷应激、缺氧、紫外线照射 …

冷诱导rna结合蛋白在机体的主要组织器官中广泛表达，是位于细胞核内的rna伴侣蛋白。近年来研究证实，冷诱导rna结合蛋白（cirp）可从损伤的组织细胞中释放至细胞外，作为损伤相关分子 …

2018年4月4日 · We here identify cold-inducible RNA-binding protein (CIRP) (A18 hnRNP, Cirbp) as a novel p27 mRNA-binding protein. CIRP is composed of a conserved N-terminal RNA …

2022年5月12日 · 首先观察Input组，第一块胶图是利用Anti-Flag检测Flag标签，结果显示第二泳道和第三泳道均检测到条带，说明第二组和第三组实验都存在A-3×Flag蛋白；第二块胶图是利 …

2021年3月23日 · Cold‐inducible RNA‐binding protein (CIRP) was a crucial regulator in multiple diseases. However, its role in pulmonary artery hypertension (PAH) is still unknown. Here, we …

2015年8月28日 · Cold-inducible RNA-binding protein (CIRP) was initially screened as a gene transcript that is induced by DNA damage and plays a key role in controlling various cellular …

CIRP binds directly to the telomerase RNA template TERC. The two RNA-binding domains of CIRP, the N-terminal RRM and C-terminal RGG motifs have both been demonstrated to bind …

Cold-inducible RNA binding protein (CIRBP) is a stress-responsive protein that promotes cancer development and inflammation. Critical to most CIRBP functions is its capacity to bind and …

CIRP (and flag) expression in CIRP overexpression or vehicle-treated AtT20 cells. Fig. S3 A, Secreted ACTH levels with and without CRH stimulation in vehicle or CIRP-overexpressing …