NGAL in chronic kidney disease: clinical studies. As discussed above, NGAL is a promising biomarker of AKI. In CKD, there is a growing literature suggesting that NGAL is also a marker …

2022年11月1日 · Neutrophil Gelatinase Associated Lipocalin (NGAL) is a secretory protein of neutrophils that can be found both in plasma and urine. Previous works have demonstrated a …

Studies in the domestic and abroad have revealed that during the initiation and development of kidney disease such as acute kindey injury (AKI) and chronic kidney disease (CKD), changes …

急性肾损伤（AKI）是一种涉及多学科的临床常见危重病，由多种病因造成肾功能在短期内急性减退，临床上对AKI也不是无计可施，NGAL成为发现AKI的早期标志物。 什么是NGAL? 名 …

2024年7月30日 · 研究显示，慢性肾病（ckd）患者尿液、血浆中的ngal水平显著高于正常人群，并与肾小球滤过率(gfr)及肾实质损伤的严重程度密切相关，因此，ngal可作为评价ckd患者肾脏 …

Estimated glomerular filtration (eGFR) rate was calculated by Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) formula. The patients were followed for two years to …

2020年5月26日 · We found that uNGAL measured at the onset of AKI was associated with persistent AKI, MAKE30, MAKE365, new-onset CKD, and CKD progression. Urinary NGAL …

Each 10 ng/mL higher urinary NGAL or serum NGAL was associated with a 3% (HR, 1.03; 95% CI, 1.03–1.04) and 2% (HR, 1.02; 95% CI, 1.01–1.03) higher risk for progression of CKD (31 …

2022年1月21日 · 肾功能下降可发生在原来无肾功能不全的患者，也可发生在原已稳定的慢性肾病（CKD）患者，其主要发病原因是肾灌注量减少导致血流动力学介导的肾小球滤过率降低引起 …

The evidence for the role of NGAL measurements in a variety of clinical situations leading to AKI (cardiac surgery, kidney transplantation, contrast nephropathy, haemolytic uraemic syndrome …