糖尿病和高血压是慢性肾脏病（ckd）的最常见原因，肾小管间质纤维化被认为是与 ckd 进展和肾衰竭相关的主要组织病理学表现。 然而，肾小囊脏层细胞对CKD的贡献不可低估，因为肾小球中的肾小囊脏层细胞密度是CKD进展的主要预测因素，特别是在疾病的早期 ...

2022年7月17日 · Our objectives were to determine the triglycerides/HDL-cholesterol ratio (TG/HDL-C), evaluate the correlation between TG/HDL-C and the urine albumin/creatinine ratio (ACR), and estimate the glomerular filtration rate (eGFR) according to MDRD in CKD patients.

2025年2月24日 · CKD contributes to HTG through lipolytic enzyme deficiencies, impairing lipid clearance and raising kidney damage risk. Epidemiological, experimental and genetic studies support the role of HTG in favoring renal damage and CKD progression. Inherited lipid disorders like LPG, LCAT deficiency worsen renal health.

2022年2月10日 · Chronic kidney disease (CKD) is associated with a dyslipidemia comprising high triglycerides, low HDL-cholesterol and altered lipoprotein composition. Cardiovascular diseases are the leading cause of mortality in CKD, especially in end stage renal disease patients.

2019年1月3日 · 现有证据表明，降低低密度脂蛋白胆固醇（LDL-C）有利于预防慢性肾脏病（CKD）患者和肾移植受者中的主要动脉粥样硬化事件，但对透析患者无益。 2013 年肾脏疾病改善全球预后（KDIGO）《CKD 脂质管理临床实践指南》为 CKD 和 ESRD 患者血脂异常的治疗提供了简单的建议。 针对慢性肾病患者的血脂管理问题，但来自英国伯明翰大学的 Charles J. Ferro 教授等人近期在《自然综述-肾脏病》杂志上发表了一篇综述。 （1）心血管风险与估计肾小球 …

2022年9月15日 · Our study found that elevated TG and reduced HDL-C levels are independently associated with a higher risk of CKD stages 4–5. This suggests that TG and HDL-C levels might be useful for risk stratification as well as for a potential target to reduce the risk of …

高甘油三酯血症（htg）是慢性肾脏病（ckd）患者常见的脂代谢异常，可加速ckd进展，且与心血管疾病的残余风险密切相关。 然而，目前缺乏关于肾科医师如何管理CKD合并HTG的专家共识，存在未满足的临床需求。

ckd患者是脂代谢紊乱的高危人群之一，尤以低hdl－c血症和（或）高tg血症最为常见。 甘油三脂、胆固醇和磷脂是血浆中最重要的血脂成分，胆固醇和甘油三脂不溶于水，靠磷脂和蛋白质运输，脂蛋白微粒由非极性脂质构成。

The TG/HDL-C ratio was an independent risk factor for CKD, but it showed no superiority over MAP in predicting CKD. A TG/HDL-C ratio ≥2.76 may be useful in clinical practice to detect subjects with worsened cardiometabolic profile who need monitoring to prevent CKD.

2025年3月10日 · Chronic kidney disease (CKD), one of the major non-communicable chronic diseases, is a leading cause of morbidity and mortality of the population all over the world. ... but they focused on a single measurement of TyG-BMI and neglected the long-term effects of TyG-BMI on CKD (16, 17). TG, FBG and BMI tend to be influenced by various factors ...