Chronic lymphocytic leukemia (CLL) is one the most common types of leukemia in adults. It's a type of cancer that starts in early forms of certain white blood cells (called lymphocytes) in the bone marrow.

Chronic lymphocytic leukemia (CLL) is a type of cancer that affects the blood and bone marrow. [8][9] In CLL, the bone marrow makes too many lymphocytes, which are a type of white blood cell. [8][9] In patients with CLL, B cell lymphocytes can begin to collect in their blood, spleen, lymph nodes, and bone marrow. [10][4] These cells do not ...

2023年3月7日 · Chronic lymphocytic leukemia is a chronic lymphoproliferative disorder characterized by monoclonal B cell proliferation. It is the most common adult leukemia in Western populations and comprises 25 to 30 percent of leukemias in the United States.

2024年12月20日 · Chronic lymphocytic leukemia (CLL) is a type of cancer of the blood and bone marrow — the spongy tissue inside bones where blood cells are made. The term "chronic" in chronic lymphocytic leukemia comes from the fact that this leukemia typically progresses more slowly than other types of leukemia.

Chronic lymphocytic leukaemia (CLL) is a malignancy of CD5 + B cells that is characterized by the accumulation of small, mature-appearing neoplastic lymphocytes in the blood, marrow and secondary lymphoid tissues, resulting in lymphocytosis, leukaemia cell infiltration of the marrow, lymphadenopathy and splenomegaly.

Chronic lymphocytic leukemia (CLL) is the most frequent type of leukemia. It typically occurs in older patients and has a highly variable clinical course. Leukemic transformation is initiated by specific genomic alterations that interfere with the regulation of proliferation and apoptosis in …

5 天之前 · Chronic lymphocytic leukemia (CLL) is a slow-growing blood cancer involving the abnormal overgrowth of a type of white blood cell called B-lymphocytes. In CLL, not only are too many abnormal B-lymphocytes produced, but the cancerous cells also live longer than healthy B-lymphocytes do.

2025年1月30日 · Chronic lymphocytic leukaemia (CLL) is a type of slow-growing leukaemia that affects developing B-lymphocytes. B lymphocytes (also known as B-cells) are specialised white blood cells. Under normal conditions they produce immunoglobulins (also called antibodies) that help protect our bodies against infection and disease.

2025年3月12日 · Chronic lymphocytic leukemia (CLL) is a relatively indolent hematologic malignancy of mature CD19 + CD5 + B cells. CLL cells exhibit increased dependence on free fatty acid oxidation (FAO) for energy compared to normal B cells [1]. Fatty acid metabolism has implications for drug resistance in CLL, with ibrutinib resistance linked to FAO and abnormal phospholipid levels associated with ...

Chronic lymphocytic leukemia (CLL) is characterized by progressive accumulation of phenotypically mature malignant B lymphocytes. Primary sites of disease include peripheral blood, bone marrow, spleen, and lymph nodes.