CNPase is a myelin -associated enzyme that makes up 4% of total CNS myelin protein, and is thought to undergo significant age-associated changes. [7] It is named for its ability to catalyze …

神经元是中枢神经系统 (CNS) 和周围神经系统 (PNS) 中的电兴奋细胞，它们传送并接收电脉冲和神经化学信号以处理信息。 神经元驱动脑、脊髓、外周感觉和运动系统中的活动。 它们是高 …

2016年6月15日 · CNPase is a peripheral membrane protein containing two folded domains and a lipidated tail. It has a specific enzymatic activity first discovered 60 years ago (Drummond et …

The membrane-anchored myelin enzyme 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNPase) was discovered in the early 1960s and has since then troubled scientists with its peculiar …

2012年2月29日 · CNPase is a member of the 2H phosphoesterase family and catalyzes the formation of 2′-nucleotide products from 2′,3′-cyclic substrates; however, its physiological …

2015年11月13日 · 2′,3′-cyclic nucleotide 3′-phosphodiesterase (CNPase) is an enzyme highly abundant in the central nervous system myelin of terrestrial vertebrates. The catalytic domain...

2024年12月10日 · 2′,3′-Cyclic nucleotide 3′-phosphodiesterase (CNPase) is an abundant constituent of central nervous system non-compact myelin, and its loss in mice and humans …

2'2'—环核苷酸3'—磷酸二酯酶 (CNPase)是一种髓鞘标志酶,主要存在于CNS髓鞘,其他组织中活性很低.动物实验及临床研究表明,当CNS发生脱髓鞘损害时,CNS髓鞘中CNPase活性降 …

2015年9月15日 · 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNPase) is an abundant membrane-associated enzyme within the vertebrate myelin sheath. While the physiological …

2′,3′-cyclic nucleotide-3′-phosphodiesterase (CNPase) is a myelin-associated enzyme that catalyzes the phosphodiester hydrolysis of 2’,3’-cyclic nucleotides to 2’-nucleotides. However, …