Contactin-associated protein-like 2 is a protein that in humans is encoded by the CNTNAP2 gene. [5] [6] [7] This gene encodes a member of the neurexin family which functions in the vertebrate …

2024年12月24日 · CNTNAP2 (Contactin Associated Protein 2) is a Protein Coding gene. Diseases associated with CNTNAP2 include Pitt-Hopkins-Like Syndrome 1 and Autism 15. …

2023年6月5日 · 接触蛋白相关蛋白样2的编码基因（Contactin-associated protein-like 2， CNTNAP2）是一个被广泛验证的孤独症易感基因， CNTNAP2 基因敲除小鼠（Cntnap2-/-） …

The CNTNAP2 gene encodes Contactin-associated protein 2 or CASPR2, a neuronal cell-adhesion protein. CNTNAP2 is the largest gene in the human genome. In the brain and the …

2024年3月1日 · Mutations in the Contactin-associated protein-like 2 (CNTNAP2) gene are associated with autism spectrum disorder (ASD), and ectodomain shedding of the CNTNAP2 …

2025年2月8日 · CNTNAP2 gene has been found to be associated with language disorders and sequential learning and phonological buffer's performances. Mutations in CNTNAP2 have …

2022年2月16日 · Among shed synaptic proteins is the ectodomain of CNTNAP2 (CNTNAP2-ecto), a prominent NDD risk factor. CNTNAP2 undergoes activity-dependent ES via MMP9 …

2023年6月5日 · CNTNAP2 is a single transmembrane protein of Neurexin superfamily, localized in the post-synaptic region with a large extracellular domain and a short intracellular domain. …

2013年5月29日 · This review considers the evidence implicating CNTNAP2 in these conditions, the genetic risk factors and mutations that have been identified in patient and population …

Contactin-associated protein-like 2 (CNTNAP2) is a large multidomain neuronal adhesion molecule implicated in a number of neurological disorders, including epilepsy, schizophrenia, …