COL4A3 Gene - GeneCards | CO4A3 Protein | CO4A3 Antibody
2024年12月24日 · COL4A3 (Collagen Type IV Alpha 3 Chain) is a Protein Coding gene. Diseases associated with COL4A3 include Alport Syndrome 3A, Autosomal Dominant and Alport …
IV 型胶原α3 链（COL4A3）基因 | MCE - MCE-生物活性分子大师
IV 型胶原蛋白是基底膜的主要结构成分，是由 3 个 α 亚基组成的多聚体蛋白。 这些亚基由 6 个不同的基因编码，从 alpha 1 到 alpha 6，每个基因都可以与其他 2 个亚基形成三螺旋结构，形 …
Collagen, type IV, alpha 3 - Wikipedia
Collagen alpha-3(IV) chain is a protein that in humans is encoded by the COL4A3 gene. [5] [6] Type IV collagen, the major structural component of basement membranes, is a multimeric …
COL4A3 collagen type IV alpha 3 chain [ (human)] - National …
COL4A3 overexpression in podocytes caused chain retention in the endoplasmic reticulum associated with activation of the unfolded protein response. Mutant COL4A3 chains …
COL4A3 gene - MedlinePlus
The COL4A3 gene provides instructions for making one piece of a protein called collagen IV. Specifically, this gene makes the alpha3 (IV) chain of collagen IV. This chain combines with …
Entry - *120070 - COLLAGEN, TYPE IV, ALPHA-3; COL4A3 - OMIM
Type IV collagen is found only in basement membranes, where it is the major structural component. COL4A3 is 1 of 6 alpha chains that form the heterotrimeric type IV collagen …
IV型胶原蛋白 - 知乎 - 知乎专栏
它由六个不同的基因编码： IV型胶原蛋白 α1 (COL4A1)、 COL4A2 、 COL4A3 、 COL4A4 、 COL4A5 和 COL4A6。 1.临床意义. IV型胶原蛋白可维持细胞分裂和生长。 胶原蛋白分泌异常 …
Heterozygous Pathogenic COL4A3 and COL4A4 Variants …
Multiple unselected cohorts with ESKF have found heterozygous pathogenic variants in COL4A3 and COL4A4 occur about as often as COL4A5 variants, which suggests that AD Alport …
COL4A3 collagen type IV alpha 3 chain - NIH Genetic Testing …
Type IV collagen, the major structural component of basement membranes, is a multimeric protein composed of 3 alpha subunits. These subunits are encoded by 6 different genes, alpha 1 …
Col4a3小鼠基因|Col4a3基因功能|Col4a3小鼠模型-RDDC官网
这个基因的人类同源物与Alport综合征；常染色体显性Alport综合征；常染色体隐性Alport综合征；良性家族性血尿；和终末期肾病有关。 与人类的COL4A3（胶原类型IVα3链）正交。 [由基 …