
CCP110 Gene - GeneCards | CP110 Protein | CP110 Antibody
2024年12月24日 · CCP110 (Centriolar Coiled-Coil Protein 110) is a Protein Coding gene. Diseases associated with CCP110 include Spinocerebellar Ataxia 11 and Female-Restricted Syndromic X-Linked Intellectual Disability 99. Among its related pathways are Loss of proteins required for interphase microtubule organization from the centrosome and Cell Cycle, Mitotic.
CP110 Non-Display On-Site Two-Way Radio - Motorola Solutions
The CP110 non-display two-way radio operates on 89 UHF or 27 VHF business-exclusive frequencies and is 2013 FCC Narrowband ready. The default factory programming on this CP110 radio is set to operate in 12.5kHz mode.
CCP110 - Wikipedia
Centriolar coiled-coil protein of 110 kDa also known as centrosomal protein of 110 kDa or CP110 is a protein that in humans is encoded by the CCP110 gene. It is a cell cycle -dependent CDK substrate and regulates centrosome duplication.
CP110, a cell cycle-dependent CDK substrate, regulates …
Our data suggest that CP110 is a physiological centrosomal CDK target that promotes centrosome duplication, and its deregulation may contribute to genomic instability. Centrosome duplication and separation are linked inextricably to certain cell cycle events, in particular activation of cyclin-dependent kinases (CDKs).
Centrosomal protein CP110 controls maturation of the mother …
Centriolar coiled coil protein 110 (CP110) caps the distal end of the mother centriole and is known to act as a suppressor to control the timing of ciliogenesis. Here, we demonstrate that CP110 promotes cilia formation in vivo, in contrast to findings in cultured cells.
9738 - Gene ResultCCP110 centriolar coiled-coil protein 110
CP110 plays a mechanistic role in response of lung cancer cells to CDK2 inhibition, especially in the presence of activated KRAS mutations. Centrin2 regulates primary ciliogenesis through controlling CP110 levels.
Cep97 and CP110 suppress a cilia assembly program - PubMed
2007年8月24日 · Depletion of Cep97 or expression of dominant-negative mutants results in CP110 disappearance from centrosomes, spindle defects, and polyploidy. Remarkably, loss of Cep97 or CP110 promotes primary cilia formation in growing cells, and enforced expression of CP110 in quiescent cells suppresses their ability to assemble cilia, suggesting that ...
CP110, a Cell Cycle-Dependent CDK Substrate, Regulates …
2001年11月2日 · In this report, we describe the isolation of an uncharacterized human protein, CP110, which is phosphorylated in vitro and in vivo by CDKs that function during S phase and in subsequent phases of the cell cycle. The abundance of CP110 is regulated during the cell cycle, peaking during S phase and diminishing thereafter.
LUBAC regulates ciliogenesis by promoting CP110 removal from
2022年1月3日 · The CP110-CEP97 complex removal from the mother centriole is an early critical step for ciliogenesis, but the underlying mechanism for this step remains largely obscure. Here, we reveal that the linear ubiquitin chain assembly complex (LUBAC) plays an essential role in ciliogenesis by targeting the CP110-CEP97 complex.
Ccp110 centriolar coiled coil protein 110 [ (house mouse)]
2025年2月8日 · CP110 loss resulted in an abnormal distribution of core components of subdistal appendages and of recycling endosomes, which may be associated with premature extension of axonemal microtubules. CP110 has unique context-dependent functions, acting as both a suppressor and a promoter of ciliogenesis.
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