犬细小病毒VP2在免疫反应中的作用 - 搜狐
2018年11月11日 · 什么是vp2？ VP2是构成衣壳蛋白的主要成分，是CPV的免疫原性蛋白，编码CPV的主要抗原决定簇。 VP2蛋白长度为584个氨基酸，分子量大小约64.58kDa, 等电点(pI) …
Canine parvovirus (CPV) phylogeny is associated with disease …
2019年8月2日 · The present study rejects the antigenic variant concept and attempts to evaluate the association between CPV strain phylogeny, reconstructed using the whole information …
犬细小病毒（CPV）疫苗接种和免疫失败：我们离该疾病根除还很 …
最初的毒株被命名为犬细小病毒 2 型 (CPV-2)，以区别于基因和抗原无关的犬细小病毒 1 型（CPV-1 或犬微小病毒），后者已被重新分类为食肉动物博卡帕沃病毒 1（博卡帕沃病毒 …
Evolutionary and genetic analysis of the VP2 gene of canine …
2017年7月17日 · To analyze the genetic diversity and evolution dynamics of CPV, we collected 424 full-length VP2 sequences of CPV obtained over a period of 38 years (from 1979 to 2016) …
Molecular Analysis of Full-Length VP2 of Canine Parvovirus …
The current study represents the first molecular, amino acid, and pressure selection characterization of the complete CPV VP2 gene in Chile. Phylogenetic analysis revealed that …
犬细小病毒VP2蛋白特点及病毒样颗粒疫苗制备研究进展-【维普期 …
通过构象分析得知CPV VP2蛋白环状结构 (Flexible loop)具有更大的灵活性,这可能是CPV感染宿主范围不断扩大的分子基础。 同时笔者对VLPs疫苗的制备方法及优缺点进行讨论,以期为CPV疫 …
Study of the immunogenicity of the VP2 protein of canine …
2020年6月18日 · Full length CPV VP2 protein was expressed at high level and purified efficiently. Moreover, it stimulated mice to produce high level of antibodies with hemmaglutination …
Immunodetection of Canine Parvovirus (CPV) in clinical samples by ...
The entire virion protein 2 (VP2) gene of Canine Parvovirus (CPV) was amplified by polymerase chain reaction (PCR) and engineered to be expressed by a bacterial expression vector pET …
Whole genome sequence analysis of CPV-2 isolates from 1998 to …
2023年7月3日 · VP2 is the main DNA sequence coding the capsid protein in CPV-2 and plays a crucial role in viral pathogenicity. Numerous studies reported the VP2 mutations and their …
Characterization of the VP2 and NS1 genes from canine …
In the results of CPV-2 VP2 gene alignment, CPV-2c strains harbored the key mutation sites with 370R and 440T, while new CPV-2a/2b genetic variants showed 370Q and 440A. Geng and …