016959 - Foxp3[YFP-cre] Strain Details - The Jackson Laboratory
016959 B6.129(Cg)- Foxp3 tm4(YFP/icre)Ayr /J Foxp3 YFP/cre mutant mice express a knocked-in yellow fluorescent protein/iCre-recombinase fusion protein from the Foxp3 locus without …
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Foxp3YFP-Cre
Foxp3YFP-Cre突变小鼠在不破坏内源性Foxp3基因表达的情况下，从Foxp3位 点表达敲入的YFP-cre重组酶融合蛋白。 这些小鼠可能有助于研究调节性T
FOXP3 + regulatory T cell perturbation mediated by the IFNγ
2024年1月2日 · Overall, our study demonstrates that the perturbation of tumor-infiltrating Tregs through the IFNγ-IFITM3-STAT1 feedback loop is essential for anti-tumor immunity and …
017353 - YetCre-13 Strain Details - The Jackson Laboratory
017353 C.129S4(B6)- Il13 tm1(YFP/cre)Lky /J Expression of the YFP-Cre fusion gene in these mice is observed in Il13 -expressing cells, including innate type 2 helper cells. These YetCre …
小鼠精子发生过程转录组动态变化|南模生物
南模生物为该研究构建了Lin28-YFP,Vasa-dTomato和Stra8-GFP Cre 3种小鼠。 这项工作开创性地将精子发生同步化方法与生殖细胞特异性荧光标记相结合，分离获取了高纯度的处于不同发育 …
广泛使用的Foxp3-YFP-Cre小鼠的异位种系重组活性：病例报告 …
2019年12月3日 · 为了产生缺乏胰岛素受体（Insr）表达的Treg细胞，我们将Foxp3YFP-Cre小鼠与Insrfl / fl小鼠杂交。 使用常规的两波段PCR基因分型方法，我们发现后代的基因型不符合预期的 …
Instability of the transcription factor Foxp3 leads to the generation ...
2009年7月26日 · We crossed transgenic mice expressing a green fluorescent protein–Cre recombinase fusion protein (GFP-Cre) controlled by the Foxp3 promoter on a bacterial artificial …
Genetic Tools for Analyzing Foxp3 - Springer
2022年10月1日 · In this chapter, we describe how the dual Foxp3 RFP/GFP reporter can be exploited to discriminate both developmental sublineages based on tTreg cell lineage–specific …
Transcription factor Foxp1 regulates Foxp3 chromatin binding and ...
2019年1月14日 · Our studies suggest that Foxp1 serves an essential non-redundant function in T reg cells by enforcing Foxp3-mediated regulation of gene expression and enabling efficient IL …
Ectopic germline recombination activity of the widely used Foxp3‐YFP …
Foxp3‐YFP‐cre mice are commonly used to generate regulatory T (Treg) cell‐specific knockout mice but when crossed with insulin receptor floxed mice, we found that some offspring had …