Objective: To investigate the prevalence of anti-C-reactive protein (CRP) autoantibodies in patients with systemic lupus erythematosus (SLE) and non-SLE patients with persistent antiphospholipid antibodies (aPL) and their association with clinical manifestations.

2005年11月16日 · The database we used to address this question consisted of 1051 consecutive pts with untreated AML (APL excepted) or high-risk MDS (> 10% blasts) considered for induction therapy at MDA from 2000 through 2004. 5% of the pts declined therapy, 45% achieved CR and 5% CRp, as usually defined, while 29% were resistant, i.e. they survived at least 1 ...

2005年12月13日 · Similarities were found between elevated levels of hs-CRP and the presence of antiphospholipid antibodies (aPL) for the pathology of thrombosis. Both hs-CRP and aPL influence endothelial activation and tissue factor up-regulation both of which are described as main pro-thrombotic criteria (Cermak et al., 1993; Dinarello, 1996).

High-sensitive C-reactive protein (hs-CRP) is a marker of inflammation which has been shown in several prospective studies to independently predict myocardial infarction, stroke and peripheral artery disease. Patients with antiphospholipid antibodies (aPL) are at …

2004年11月16日 · High-sensitive C-reactive protein (hs-CRP) is a marker of inflammation which has been shown in several prospective studies to predict independently myocardial infarction, stroke or peripheral artery disease.

2012年12月8日 · Antiphospholipid (aPL) syndrome (APS) is an acquired autoimmune thrombotic tendency in which patients have circulating antibodies (Abs) against plasma proteins that bind to phospholipids. The concepts of this disorder evolved through the observations of astute clinicians and much of the approach to diagnosis is based on consensus rather than on ...

2005年11月16日 · For many years response to induction therapy for AML was classified as CR or no CR. Recently, responses less than CR, e.g. CR with incomplete platelet recovery (CRp), have also been recognized. Attaining CRp suggests that a treatment is more “active” than if neither CR nor CRp had occurred (“resistant”).

2005年12月1日 · Patients with antiphospholipid antibodies (aPL) are at increased risk of recurrent thromboembolic events, but the possibility of predicting this risk seems rather limited. Similarities were...

Anti-CRP antibodies occurred markedly more frequently in patients with thrombosis or fetal loss—features of the antiphospholipid syndrome—than in asymptomatic aPL carriers, in both SLE patients...

Complement activation and low complement levels are common in systemic lupus erythematosus (SLE). Antiphospholipid antibodies (aPL) are found in about 30-40% of patients with SLE. This study aimed to investigate the association between aPL and complement levels in …